BACKGROUND Voluntary motor deficits are a common feature in Huntington's disease (HD), characterised by movement slowing and performance inaccuracies. This deficit may be exacerbated when visual cues are restricted. OBJECTIVE To characterize the upper limb motor profile in HD with various levels of difficulty, with and without visual targets. METHODS Nine premanifest HD (pre-HD), nine early...

The process of movement execution can be separated into two sections; the foreperiod and the response time. The foreperiod represents the time between the warning signal (WS) and the presentation of the imperative “go” signal, and the response time incorporates both the reaction time (RT) and the movement time (Schmidt & Lee, 2011). Transcranial magnetic stimulation (TMS) was used to probe cort...

While movement is essential to human wellbeing, we are still unable to reproduce the deftness and robustness of human movement in automatons or completely restore function to individuals with many types of motor impairment. To better understand how the human nervous system plans and controls movements, neuromechanists employ simple tasks such as upper extremity reaches and isometric force tasks...

Software supervision is an approach to the real-time detection of failures. A software supervisor is a unit which monitors both the inputs and outputs of a real-time system and reports discrepancies between observed and expected behaviors. The major diiculty with software supervision is the running-time complexity of the supervisor. A signiicant source of running-time complexity was determined ...

A tree-ensemble method, referred to as time series forest (TSF), is proposed for time series classification. TSF employs a combination of entropy gain and a distance measure, referred to as the Entrance (entropy and distance) gain, for evaluating the splits. Experimental studies show that the Entrance gain improves the accuracy of TSF. TSF randomly samples features at each tree node and has com...

Highway bridges are frequently constructed as simple span structures with steel or concrete girders and a cast-in-place concrete deck, spanning from one pier to another. At each end of the simple span deck, a joint is provided for deck movement due to temperature, shrinkage, and creep. Bridge deck joints are expensive and pose many problems with regard to bridge maintenance. Elimination of deck...

BACKGROUND Huntington disease (HD) is a genetic, neurodegenerative disorder characterized by chorea, behavioral co-morbidities, cognitive deficits, and eye movement abnormalities. We sought to evaluate whether reflexive and voluntary orienting prove useful as biomarkers of disease severity in HD. METHODS Eleven HD subjects were evaluated with the motor subscale of the Unified Huntington Disea...

the time-optimal trajectory for an airplane from some starting point to some final point is studied by many authors. here, we consider the extension of robot planer motion of dubins model in three dimensional spaces. in this model, the system has independent bounded control over both the altitude velocity and the turning rate of airplane movement in a non-obstacle space. here, in this paper a g...