We consider the estimation of joint causal effects from observational data. In particular, we propose new methods to estimate the effect of multiple simultaneous interventions (e.g., multiple gene knockouts), under the assumption that the observational data come from an unknown linear structural equation model with independent errors. We derive asymptotic variances of our estimators when the un...

Cost-based metrics formalize notions of distance, or dissimilarity, between two spike trains, and are applicable to single- and multineuronal responses. As such, these metrics have been used to characterize neural variability and neural coding. By examining the structure of an efficient algorithm [Aronov D, 2003. Fast algorithm for the metric-space analysis of simultaneous responses of multiple...

Multi-adjoint logic programs were recently proposed as a generalization of monotonic and residuated logic programs, in that simultaneous use of several implications in the rules and rather general connectives in the bodies are allowed. In this work, the need of biresiduated pairs is justified through the study of a very intuitive family of operators, which turn out to be not necessarily commuta...

T salesman problems with profits (TSPs with profits) are a generalization of the traveling salesman problem (TSP), where it is not necessary to visit all vertices. A profit is associated with each vertex. The overall goal is the simultaneous optimization of the collected profit and the travel costs. These two optimization criteria appear either in the objective function or as a constraint. In t...

Let $R$ be a ring and $M$ a right $R$-module. We call $M$, coretractable relative to $overline{Z}(M)$ (for short, $overline{Z}(M)$-coretractable) provided that, for every proper submodule $N$ of $M$ containing $overline{Z}(M)$, there is a nonzero homomorphism $f:dfrac{M}{N}rightarrow M$. We investigate some conditions under which the two concepts coretractable and $overline{Z}(M)$-coretractable...

One of the most practical routine tests for convergence of a positive series makes use of the ratio test. If this test fails, we can use Rabbe's test. When Rabbe's test fails the next sharper criteria which may sometimes be used is the Bertrand's test. If this test fails, we can use a generalization of Bertrand's test and such tests can be continued innitely. For simplicity, we call ratio test,...

In ref. we developed a unitary gauge invariant effective Lagrangian model including the final states γN , πN , 2πN , ηN , KΛ, and KΣ (ref.) for a simultaneous analysis of all avaible experimental data for photonand pion-induced reactions on the nucleon. In ref. this analysis was extended to K induced reactions. In this paper we discuss an extension of this method to vector meson nucleon final s...

This paper introduces a generalization of the nvalue constraint that bounds the number of distinct values taken by a set of variables.The generalized constraint (called nvector) bounds the number of distinct (multi-dimensional) vectors. The first contribution of this paper is to show that this global constraint has a significant role to play with continuous domains, by taking the example of sim...

We consider a generalization of the uncapacitated facility location problem that occurs in planning of optical access networks in telecommunications. Clients are connected to open facilities via depthbounded trees. The total demand of clients served by a tree must not exceed a given tree capacity. We investigate a framework for combining facility location algorithms with a tree-based clustering...