OBJECTIVE To create an ideal temporary skin substitute. METHODS Temporary skin substitute (Biobrane, AWBAT and AWBAT Plus) porosity, 3D matrix, and biochemical composition were evaluated for impact on healing wounds (pain, fluid accumulation, infection, and time to heal). Twenty-four Sprague-Dawley [H1a: (SD) CVF] rats were used to measure the histology of healed full-thickness wounds. Tissue...

In the last decade, a new class of natural biomaterials derived from de-fatted soybean flour processed by either thermoset or extraction procedures has been developed. These biomaterials uniquely combine adaptability to various clinical applications to proven tissue regeneration properties. In the present work, the biomaterials were formulated either as hydrogel or as paste formulation and thei...

Hypospadias is the most common penile congenital anomaly [2] and the second most common congenital malformation in males, occurring in approximately one in 125 live male births [3]. Two theories were suggested for development of hypospadias, endodermal theory and ectodermal theory [4]. Types of hypospadias are anterior, middle and posterior with the posterior type account approximately 20% of c...