OBJECTIVE To evaluate the potential utility of the Sniff Magnitude Test (SMT) as a clinical measure of olfactory function. DESIGN Between-subject designs were used to compare the SMT and University of Pennsylvania Smell Identification Test (UPSIT) in study participants from a broad range of ages. SUBJECTS A total of 361 individuals from retirement communities and an urban university and pat...

OBJECTIVE To compare olfactory function in vascular parkinsonism and Parkinson's disease diagnosed according to published clinical diagnostic criteria. METHODS The University of Pennsylvania smell identification test (UPSIT) was carried out in 14 patients with vascular parkinsonism, 18 with Parkinson's disease, and 27 normal controls matched for age, sex, and smoking status. RESULTS UPSIT s...

BACKGROUND A positive effect of Endoscopic Sinus Surgery (ESS) as sole treatment on olfactory thresholds and sense of smell in patients with nasal polyposis has been questioned. The aim of this study was to test the hypothesis that ESS has a positive effect on sense of smell and olfactory threshold in nasal polyposis. METHODS Uncontrolled post-hoc analysis of a prospective study of 160 patien...

Scores on the University of Pennsylvania Smell Identification Test (UPSIT), as well as the numbers of MRI-determined plaques within the inferior frontal and temporal lobes, were obtained on three or four separate occasions in each of five MS patients over an 18- to 20-month period. A close association was observed, longitudinally, between the remission and exacerbation of plaque numbers and UPS...

INTRODUCTION Sensory factors may play an important role in the determination of appetite and food choices. Also, some adipokines may alter or predict the perception and pleasantness of specific odors. We aimed to analyze differences in smell-taste capacity between females with different weights and relate them with fat and fat-free mass, visceral fat, and several adipokines. MATERIALS AND MET...

The olfactory system and emotional systems are highly intervened and share common neuronal structures. The current study investigates whether emotional (e.g., anger and fear) and physiological (saliva cortisol) stress responses are associated with odor identification ability and hedonic odor judgments (intensity, pleasantness, and unpleasantness). Nineteen men participated in the modified Trier...

Mexico City (MC) residents are exposed to severe air pollution and exhibit olfactory bulb inflammation. We compared the olfactory function of individuals living under conditions of extreme air pollution to that of controls from a relatively clean environment and explore associations between olfaction scores, apolipoprotein E (APOE) status, and pollution exposure. The olfactory bulbs (OBs) of 35...

After a total laryngectomy the upper and lower airways are disconnected resulting in a wide range of adverse effects, e.g. deterioration of nasal functions in breathing, loss or decrease of normal sense of smell and taste, as well as loss of normal voice. Recently, a new method that can restore the sense of smell in laryngectomized patients has been developed, the Nasal Airflow-Inducing Maneuve...

OBJECTIVE This study aimed to research the normative values of olfactory function in the Turkish population using the Sniffin' Sticks test and to relate olfactory performance to age, sex, smoking, educational level, and the side examined. It also aimed to compare the results with other countries' normative values, especially Europe, using the same test and procedure. STUDY DESIGN Prospective ...

OBJECTIVE To resolve whether the olfactory pathways are affected in multiple sclerosis. METHODS Olfaction was assessed by: (1) The University of Pennsylvania smell identification test (UPSIT, which uses microencapsulated odours that are released when scratched with a pencil) in 72 patients with multiple sclerosis and 96 controls, (2) olfactory evoked potentials (OEP) to 20 ppm H2S by volume, ...