IMPORTANCE Patients with chronic rhinosinusitis (CRS) have reduced sleep quality linked to their overall well-being and disease-specific quality of life (QOL). Other primary sleep disorders also affect QOL. OBJECTIVE To determine the impact of comorbid obstructive sleep apnea (OSA) on CRS disease-specific QOL and sleep dysfunction in patients with CRS following functional endoscopic sinus sur...

Introduction:  Eosinophilic mucin rhinosinusitis is a type of chronic rhinosinusitis (CRS). Diagnosis and treatment of this condition play a significant role in reducing the patients’ clinical symptoms. This type of rhinosinusitis has a higher relapse rate, compared to the other types. This disease is more resistant to treatment and more dependent on corticosteroid therapy, compared to the oth...

Introduction: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a relatively common disease with serious impacts on patient quality of life. Recurrence of polyps after functional endoscopic sinus surgery (FESS) is a dilemma. Vitamin D3 (VD3) is known to inhibit the proliferation of nasal polyp-derived fibroblasts. The present study aimed to investigate the effects of oral VD3 on the...

Background Sinonasal disease is significantly prevalent in the adult community, this research explores its prevalence within the 11-16 age group in London, UK and in Lahore, Pakistan. Epidemiological assessment was accompanied by assessment of associated compliactions. The Sino-Nasal Outcome Test -20 (SNOT-20) questionnaire, a disease related quality of life instrument, was modified for use in ...

BACKGROUND The goal of this study is to compare quality of life (Qol) and symptoms in 91 patients with a deviated nasal septum preoperatively and postoperatively with a control group of 93 healthy individuals. METHODS All patients reported Qol on Sino-Nasal-Outcome-Test-20 (SNOT-20) and symptoms on visual analogue scale (VAS) preoperatively and 6 months after surgery and the results were comp...

OBJECTIVE The primary objective was to assess the long-term effectiveness of balloon catheter sinusotomy. METHODS Patients who had sinus ostia dilated with balloon catheters were prospectively evaluated 1 year after surgery with nasal endoscopy, a CT scan, and the Sino-Nasal Outcome Test (SNOT-20). RESULTS Sixty-six patients (202 sinuses) were examined. One hundred seventy-two of 202 sinus ...

Introduction Dupilumab is the first approved antibody-based systemic add-on treatment option in Germany for severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP). The aim of this study to compare and evaluate response patients treated dupilumab 300mg every 2 weeks our clinic since 2019 based on some parameters necessary indication monitoring therapy better assess impact therapy....

Background: Firefighters are often exposed to high temperatures and by-products of combustion, which can compromise their health. We aimed evaluate the effect fire exposure in simulators on airways firefighters at different time-points. Methodology: Thirty-seven male were evaluated three phases: pre-exposure, end first week, 4 weeks after. Pulmonary function by spirometry, nasal mucociliary cle...

Chronic rhinosinusitis (CRS) is not a life-threatening disorder but may have a great impact on the patients. This study intended to evaluate the impact of functional endoscopic sinus surgery (FESS), and compare the effect and quality of life (QOL) after two different surgical approaches on patients with CRS. Sixty patients of CRS were analyzed before and after FESS. The extent of disease was ev...