Upconversion nanocrystals represent a new class of nonlinear optical materials that can convert low energy radiation into higher energy radiation. Recent advances in synthesis techniques have produced nanocrystals with controllable size and color emission as well as novel surface properties that enable such attributes as water solubility and biological functionality. This in turn has led to an ...

A series of 1,3-benzoxazole-4-carbonitriles was synthesized and evaluated for its antifungal activity, solubility, and metabolic stability. Among those compounds, 4-cyano-N,N,5-trimethyl-7-[(3S)-3-methyl-3-(methylamino)pyrrolidin-1-yl]-6-phenyl-1,3-benzoxazole-2-carboxamide (16b) exhibited potent in vitro activity against Candida species, higher water solubility, and improved metabolic stabilit...

This paper reports physicochemical studies in fungal infected galls of Pongamia pinnata. The parameters assayed were Total ash, acid insolubility and water solubility values and extractive values (Alcohol, water and petroleum ether). Fungal infected galls showed significantly higher value of ash, acid insolubility and low water solubility and high extractive values (petroleum ether and water) w...

Because of the high water solubility in wadsleyite and ringwoodite, the mantle transition zone is possibly a large water reservoir. The potentially high water content of the Earth's mantle transition zone is a key element of several global mantle dynamic models. Nevertheless, to keep the transition zone relatively wet, the tendency for convection to distribute water over the entire mantle has t...

Plate tectonics is based on the concept of rigid lithosphere plates sliding on a mechanically weak asthenosphere. Many models assume that the weakness of the asthenosphere is related to the presence of small amounts of hydrous melts. However, the mechanism that may cause melting in the asthenosphere is not well understood. We show that the asthenosphere coincides with a zone where the water sol...

The synthesis of four new analogues of motexafin gadolinium (MGd), a gadolinium(III) texaphyrin complex in clinical trials for its anticancer properties, is described. These new derivatives contain either 1,2-diaminobenzene or 2,3-diaminonaphthalene subunits as the source of the imine nitrogens and bear multiple 2-[2-(2-methoxyethoxy)ethoxy]ethoxy (PEG) groups, on either meso aryl or beta-pyrro...

Low solubility compounds show dissolution rate limited absorption and hence poor absorption, distribution and target organ delivery. Improvement of aqueous solubility in such a case is valuable goal to improve therapeutic efficacy. Complexation with CDs by different methods like physical mixing, melting, kneding, spray drying, freeze drying, co-evaporation has been reported to enhance the solub...

The solubility of elemental mercury (Hg') at temperatures between 30 and 210°C was determined by direct sampling of mercury saturated water contained in a fixed volume stainless steel autoclave. The temperature dependence of the solubility was best represented by the equation log,^^, = -11.879 + 0.01206T where xHg is the mole fraction of dissolved Hgo and T is the temperature in degrees Kelvin....