abstract alzheimer’s disease (ad) is the most common form of dementia has become one of the most severe progressive socio-economical and medical burdens facing countries all over the world. the drugs are currently available just able to delay the symptom progression of disease. this study try to evaluate protein profile of the effects of aqueous extract of lavender ( lavandula angustifolia ) on...

background: sex steroids and their receptors exist in hippocampus and affect spatial learning and memory. this study was designed to measure testosterone level of ca1 and to assess the effect of spatial learning on its amount in left and right hippocampus of adult male rats. methods: sixteen rats were divided into two intact and castrated groups, and then trained in morris water maze (mwm). ano...

Background & Objective:  Post traumatic stress disorder (PTSD) is an anxiety reaction, which occurs as a result of encountering a seriously traumatic event during one’s lifetime. The aim of this study was to evaluate the effect of saffron aqueous extract and crocin on spatial memory and learning with the Barnes maze in a PTSD model on male Wistar rats (Weighting 200–250 gr). Materials & Method...

introduction: previous studies have shown that vitamin a and its derivatives such as retinoid and all-trans retinoic acid have a crucial role in memory, learning and synaptic plasticity. the receptors of vitamin a are seen in different parts of the brain such as hippocampus, where vitamin a has an important role in learning. in this study, the effect of intrahippocampal (ca1) injection of all –...

Lead (Pb2+) is a well known neurotoxin that was frequently found in the environment and chronic exposure to lead has been matter of public health. In the present study the effect of lead on spatial memory in developmentally exposed rats and their dams in Morris water maze task were investigated. Female rats were divided into three groups and two groups exposed to 250 and 750 part per million (p...

Background & Aims: Memory and its role in learning have long been of interest to humans. Therefore, human beings have always sought ways to enhance their memory and reduce its deficit. In the present study, the effect of pumpkin seed extract on memory and learning in adult male rats were studied. Methods: The rats (weighing 180-220 g) were divided into 7 groups (n = 8); control, sham (control a...

aging has negative effects on motor and cognitive functions, so it is essential to identify appropriate strategies to prevent the decrease of motor and cognitive functions. the aim of this research was to investigate the effect of vitamin e supplement on motor activity and spatial learning in aged rats. 36 male albino – wistar aged rats were assigned to three groups of control, vitamin e and sh...

Introduction: Exposure to 3, 4- methylenedioxymethamphetamine (MDMA) could lead to serotonergic system toxicity in the brain. This system is responsible for learning and memory functions. Studies show that MDMA causes memory impairment dose-dependently and acutely. The present study was designed to evaluate the chronic and acute effects of MDMD on spatial memory and acquisition of passive avoid...

Lead (Pb2+) is a well known neurotoxin that was frequently found in the environment and chronic exposure to lead has been matter of public health. In the present study the effect of lead on spatial memory in developmentally exposed rats and their dams in Morris water maze task were investigated. Female rats were divided into three groups and two groups exposed to 250 and 750 part per million (p...