Vitamin E (vit. E) is an antioxidant compound with different kinds including tocopherols and tocotrienols. The major sources of vit. E are vegetable and seed oils. The recommended dietary allowances vary with age, gender, and state of the person. There have been numerous experiments showing beneficial effects of vit. E on immune system, cancer, and coronary artery diseases in the elderly. Moreo...

conclusions the role of exercise is greater in the retention than the acquisition phase for recalling past experiences. background stress induced by sleep deprivation can cause degradation of learning in the acquisition phase, and low-intensity exercise can prevent the negative effects of stress. results the results showed that, after seven days of aerobic exercise on a treadmill, the experimen...

We examined the effects of both the metabotropic glutamate receptor (mGluR) antagonist MCPG and the agonist tADA in two behavioral paradigms in rats: (1) brightness discrimination and (2) spatial alternation. Compounds were applied intracerebroventricularly at different times, either 30 min prior to training or immediately after training, and rats were tested for retention 24 hr later in the sa...

Objective(s) Learning is defined as the acquisition of information and skills, while subsequent retention of that information is called memory. The objective of the present study was to investigate the effect of aqueous extract of Boswellia papyrifera on learning and memory paradigms in mice and rats. Materials and Methods This study was held at the Department of Pharmacology, Faculty of Pha...

PURPOSE Uncontrolled radiation exposure due to radiological terrorism, industrial accidents or military circumstances is a continuing threat for the civilian population. Age plays a major role in the susceptibility to radiation; younger children are at higher risk of developing cognitive deterioration when compared to adults. Our objective was to determine if an exposure to radiation affected t...

Objective: According to the declarative/procedural model, the semantic aspect of language depends on the brain structures responsible for declarative memory. The word pairs task is a common tool for evaluating declarative memory. The current study aimed to design a valid and reliable task for evaluating declarative memory in Persian children at learning and retention stages and to investigate i...

Procedural and declarative memory systems are postulated to interact in either a synergistic or a competitive manner, and memory consolidation appears to be a highly critical stage for this process. However, the precise cellular mechanisms subserving these interactions remain unknown. To investigate this issue, 24-h retention performances were examined in mice given post-training intrahippocamp...

Introduction: Epilepsy is a chronic neurological disorder in which patients experience spontaneous recurrent seizures and deficiency in learning and memory. Although the most commonly recommended therapy is drug treatment, some patients do not achieve adequate control of their seizures on existing drugs. New medications with novel mechanisms of action are needed to help those patients whose sei...

introduction: there are evidences showing the role of nitric oxide in the opiate reward properties. the role of nitric oxide signaling pathway as an intracellular mechanism on augmentation of long term potentiation in hippocampal ca1 area of rats is also confirmed. it has been also reported that oral morphine dependence facilitates formation of spatial learning and memory via activation of nmda...