BACKGROUND Overuse of antibiotics contributes to the development of antimicrobial resistance. OBJECTIVE This study aims to assess the condition of antibiotic use at health facilities at county, township and village levels in rural Guangxi, China. METHODS We conducted a cross-sectional study of outpatient antibiotic prescriptions in 2014 for children aged 2-14 years with upper respiratory in...

Background and Objectives: Since the fluoroquinolones are the broad-spectrum antibiotics, they affect both Gram-negative and Gram-positive bacteria. These antibiotics are widely prescribed by physicians. As a result, some bacteria, especially Enterobacteriaceae, have shown a resistance to this family of antibiotics. The current study a...

Broad-spectrum antibiotics are the mainstay of therapy for patients with Crohn's disease (CD) who present with localized peritonitis due to a microperforation bacterial overgrowth secondary to chronic strictures. They are essential adjuncts to drainage therapy for CD-associated abscesses and for complicated perineal disease. The lack of well-designed, placebo-controlled trials has led to much s...

Introduction: Invasive fungal sinusitis, though considered to be rare entity, is nowadays frequently encountered, not only in immunocompromised patients but also in immunocompetent patients. The changing prevalence towards immunocompetent hosts is due to the indiscriminate usage of broad spectrum antibiotics, steroids, and immunosuppressive drugs. Diagnosing invasive fungal sinusitis should not...

BACKGROUND The use of antibiotics is the single most important driver in antibiotic resistance. Nevertheless, antibiotic overuse remains common. Decline in antibiotic prescribing in the United States coincided with the launch of national educational campaigns in the 1990s and other interventions, including the introduction of routine infant immunizations with the pneumococcal conjugate vaccine ...

The prevalence of childhood obesity has been grown up since 1990s for about 3% in 2010 both in developed and developing countries. There are several factors impacting childhood weight one of which is antibiotic exposure during infancy. In the current review we aimed to assess the conducted studies regarding this topic. We searched databases such as Medline, EBSCO, Cochrane Library, Scopus with ...

b ackground: the prevalence of antibiotic resistance among extended spectrum  β-lactamase  (esbl)  producing  escherichia  coli  and  klebsiella  pneumoniae  has been increased  markedly  in recent  years. the present study was done to know the prevalence  of esbl production among isolates of e. coli and k. pneumoniae and to study the susceptibility pattern of isolates against different antibio...

The activity of daptomycin (DAP) against methicillin-resistant Staphylococcus aureus (MRSA) is enhanced in the presence of subinhibitory concentrations of antistaphylococcal β-lactam antibiotics by an undefined mechanism. Given the variability in the penicillin-binding protein (PBP)-binding profiles of different β-lactam antibiotics, the purpose of this study was to examine the relative enhance...