AIM This study aimed to analyze the effect of rat bone marrow-mesenchymal stem cells (rBM-MSCs) delivery on lesion site after spinal cord injury, and to observe the functional recovery after transplantation. MATERIAL AND METHODS MSCs were isolated from rat femurs and tibias. The experimental rat population was divided into four groups: only laminectomy (1); laminectomy+trauma (2);...

Etanercept is a tumor necrosis factor antagonist with anti-inflammatory effects. The aim of our study was to evaluate for the first time the therapeutic efficacy of in vivo inhibition of tumor necrosis factor-alpha (TNF-alpha) in experimental model of spinal cord trauma, which was induced by the application of vascular clips (force of 24 g) to the dura via a four-level T5-T8 laminectomy. Spinal...

BACKGROUND It has been stated that individuals who have spondylotic encroachment on the cervical spinal cord without myelopathy are at increased risk of spinal cord injury if they experience minor trauma. Preventive decompression surgery has been recommended for these individuals. The purpose of this paper is to provide the non-surgical spine specialist with information upon which to base advic...

Care of the combat casualty with spinal column or spinal cord injury has not been previously described, particularly in regards to spinal immobilization. The ultimate goal of spinal immobilization in the combat casualty is to first ``do no further harm'' and then provide a stable, painless spine and an optimal neurologic recovery. The protocol for treatment of the combat casualty with suspected...

Spinal cord ischemia can lead to paralysis or paraparesis, but if detected early it may be amenable to treatment. Current methods use evoked potentials for detection of spinal cord ischemia, a decades old technology whose warning signs are indirect and significantly delayed from the onset of ischemia. Here we introduce and demonstrate a prototype fiber optic device that directly measures spinal...

The thoracic spinal cords of five mongrel dogs were imaged with a 1.5 T MR scanner before and after trauma induced by a well-established method of spinal cord impaction that produces central cord hemorrhagic necrosis. The anesthetized dogs were studied acutely with a 5-in. circular surface coil, 12-cm field of view, sagittal and axial partial-saturation (TR = 600, TE = 25 msec) and spin-echo (T...

The degenerative spinal cord disease cervical spondylotic myelopathy (CSM), and caused by trauma, can result in debilitating symptoms affecting quality of life. This study used acupotomy other Korean medicine treatments (acupuncture, herbal medicine, physical therapy) to improve the CSM myelopathy. visual analog scale, modified Japanese Orthopaedic Association scale (mJOA scale), Nurick grading...

OBJECTIVE to assess the value of computed tomography in the diagnosis of cervical spine and spinal cord injuries in victims of blunt trauma. METHODS we reviewed the charts of blunt trauma victims from January 2006 to December 2008. We analyzed the following data: epidemiology, mechanism of trauma, transportation of victims to the hospital, intra-hospital care, indication criteria for CT, diag...

AIM < /B > Spinal cord injuries negatively affect the individuals and the life quality of their families due to neurological deficits caused by trauma. The prevalence of spinal cord injury is 15-45/1 million in the world. Caffeic acid phenethyl ester (CAPE) is the most active component of propolis and has neuroprotective, anti-oxidant and anti-apoptotic effects. Our aim was to determine the eff...

IntroductionSpine injury is one of the leading caused for disability in Nepal. Patients with trauma relatedspine leads to neurological dysfunction, focal deficits and even fatal life threating events.The timely intervention acute spinal could save patients from andmortality risk. Imaging modalities like Xray, CT Scan MRI helps diagnosis managementof trauma. plays crucial role detection cord sof...