Previous traditional surgery is simple removal of nucleus pulposus, but the study of Eie et al. shows high recurrence rate of lumbago and herniation after such surgery, 3 therefore, fusion internal fixation of interbody fusion cage combined with bilateral pedicle internal fixation system is often used for treatment at present, so that three-dimensional fixation can be achieved at fused lumbar s...

Background: Adjacent segment disease is a condition in which the mobile level next to fused section degenerates as result of increased biomechanical stress and mobility, it may be rostral, caudal, or both rostral caudal segment. Patients Methods: A retrospective study was conducted on 110 patients who underwent transpedicular screw fixation lumbar spine between January 2011 May 2019. Demographi...

ISP fixation has been shown to be a safe and efficacious alternative to traditional methods of posterior spinal fixation. A high degree of biomechanical stability and reliable fusion rates are achieved with preservation of adjacent level structures when using new iterations of rigid interspinous fixation. Since ISP devices do not violate adjacent facet joints, they potentially can decrease the ...

Calcium/calmodulin-dependent protein kinase II (CaMKII) plays a key role in N-methyl-D-aspartate (NMDA) receptor-dependent long-term synaptic plasticity; its location is critical for signal transduction, and may provide clues that further elucidate its function. We therefore examined the subcellular localization of CaMKII in CA1 stratum radiatum of adult rat hippocampus, by using immuno-electro...

BACKGROUND The importance of decreasing bleeding in spine surgery is not only important to maintain the patient's hemodynamic balance but also allow a better view of the surgical field. OBJECTIVES The current study aimed to compare dexmedetomidine and Esmolol™ as agents to induce hypotension in lumbar spine surgeries. PATIENTS AND METHODS A total of 50 patients aged 20 to 65 years belonging...

Tuberculosis of spine is prevalent in developing countries and is considered a disease affecting people from low socioeconomic groups [1-9]. Over the period of last three to four decades, chemotherapy for tuberculosis and various advanced surgical options which include fixation of the spinal segments with newer prosthetic implants have changed the outlook [1, 10]. Another new development in the...

In total, ~10% of chondrosarcomas arise from the mobile spine, and these are prone to local recurrence despite being low-grade malignant tumors. Almost all patients will present with pain and a palpable mass in the area of the lesion. For adequate management of the disease, an early diagnosis and careful surgical staging are important. The present study reports a case of cervical spinal low-gra...

OBJECTIVE Transpedicular instrumentation of the osteoporotic spine is a challenge for the spine surgeon due to the probability of screw loosening and the potential possibility of nonunion. The purpose of this study was to evaluate the clinical efficacy of bone cement augmented screw fixation in patients with severe osteoporosis. METHODS Between February 2004 and August 2007, 250 patients with...