Sensitive strains of Staphylococcus aureus can acquire resistance to all three of the antibiotics erythromycin, oleandomycin, and spiramycin when grown in culture media containing subinhibitory concentrations of any one of them (Jones, Nichols, and Finland, 1956). In contrast with the uniform pattern of resistance to the tetracyclines, however, staphylococci isolated from patients are often des...

OBJECTIVE To determine the effects on mother to child transmission of the timing and type of prenatal treatment, taking into account gestational age at maternal seroconversion. DESIGN Prospective cohort study. SETTING European centres offering prenatal screening for toxoplasmosis. POPULATION Children born to a cohort of pregnant women with toxoplasma infection. METHODS We determined the...

Abstract A fast reliable micellar electrokinetic methodology was investigated for the concurrent quantitation of six antimicrobial and anti-inflammatory drugs, namely, ciprofloxacin, dexamethasone, metronidazole, ornidazole, spiramycin tinidazole. The method has merits rapidity, precision, sensitivity. separation carried out in less than 7 min by applying a basic background electrolyte consisti...

Bitespiramycin, a group of 4"-O-acylated spiramycins with 4"-O-isovalerylspiramycins as the major components, was produced by recombinant spiramycin-producing strain Streptomyces spiramyceticus harboring a 4"-O-acyltransferase gene. The experiment was initially performed in synthetic medium with 0.5 g l(-1) Valine, Isoleucine or Leucine feeding at 36 h cultivation. When valine was fed, the biol...