A 39-year-old male patient presented with an extensive putrescent ulceration of abdominoperineal region infiltrated by advanced penile squamous cell carcinoma. To our knowledge, it is the largest defect after aggressive palliative resection of penile squamous cell carcinoma (pSCC) in the literature, which was 36×23 cm. The defect was divided into three sub-defects, and was repaired by bil...

Marjolin's ulcer following frostbite is a rare occurrence. Our review of literature revealed that only 23 cases have been reported. In most instances heel is involved and the most common associated malignancy is squamous cell carcinoma.We present a 69-year-old male patient with squamous cell carcinoma arising over a frostbite scar in heel 45 years after cold injury. This case is unique with res...

Salivary gland tumors, the second most common neoplasm of the mouth after squamous cell carcinoma, account for a significant proportion of tumors of the oral and perioral regions. An unusual case of adenoma presented as a solitary intraoral palatine mass in a 32-year-old woman is reported here. The tumor was interpreted as an unusual pleomorphic adenoma because of the presence of exuberant squa...

Odontogenic keratocyst (OKC) accounts for 3-11% of all odontogenic cysts. OKC is a benign intra-osseous tumor, but what makes this cyst special its aggressive behavior and high recurrence rate. relatively compared to other cysts, malignant transformation considered extremely rare. Squamous cell carcinoma associated with keratocysts have rarely been reported in the medical literature. We recentl...

introduction: squamous cell carcinoma of the oral cavity is one of the most important and common types of head and neck malignancy, with an estimated rate of 4% among all human malignancies. the aim of this study was to determine the association between expression of matrix metalloproteinase 2 and 9 and the clinicopathological features of oral squamous cell carcinoma (oscc).   materials and met...

background cervical cancer is the leading cause of death from cancer in under-developed countries. human papilloma virus (hpv) 16 and 18 are the most prevalent types associated with carcinogenesis in the cervix. conventional polymerase chain reaction (pcr), type-specific and consensus primer-based pcr followed by sequencing, restriction fragment length polymorphism (rflp) or hybridization by sp...

background: new blood vessels formation is a critical step in tumor progression. vascular density affects the clinical outcome and prognosis of malignant tumors. the aim of this study was to investigate the relation between the vascular endothelial growth factor (vegf) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (oscc).   method...

human papillomavirus (hpv) has also been suggested as an etiology of esophageal squamous cell carcinoma (scc). the aim of this study was to investigate the prevalence of hpv infection in esophageal sccs in our region with strict contamination control to prevent false positive results. thirty cases of esophageal squamous cell carcinomas were chosen by simple random selection in a period of two y...