The non-specific endonuclease inhibitor, aurintricarboxylic acid (ATA), attenuated glutamate-induced destruction of cultured cortical neurons. In part, this protective effect likely reflected the ability of ATA to produce a slowly developing block of N-methyl-D-aspartate receptor-mediated inward whole cell current or increase in intracellular free Ca2+. However, ATA also attenuated a high K(+)-...

This paper investigates Kamp-like and Büchi-like theorems for 1-clock Alternating Timed Automata (1-ATA) and its natural subclasses. A notion of 1-ATA with loop-free-resets is defined. This automaton class is shown to be expressively equivalent to the temporal logic RatMTL which is MTL[FI] extended with a regular expression guarded modality. Moreover, a subclass of future timed MSO with k-varia...

Discretization of continuous attributes is a necessary pre-requisite in deriving association rules and discovery of knowledge from databases. The derived rules are simpler and intuitively more meaningful if only a small number of attributes are used, and each attribute is discretized into a few intervals. The present research paper explores the interrelation between discretization and reduction...

Astaxanthin (ASX) is a xanthophyll pigment considered as nutraceutical with high antioxidant activity. Several clinical trials have shown the multiple health benefits of this molecule; therefore, it has various pharmaceutical industry applications. Commercial astaxanthin can be produced by chemical synthesis or through biosynthesis within different microorganisms. The molecule microorganisms hi...

The Allen Telescope Array is a multi-user instrument and will perform simultaneous radio astronomy and radio SETI (search for extra-terrestrial intelligence) observations. It is a multi-beam instrument, with 16 independently steerable dualpolarization beams at 4 different tunings. Given 4 beams at one tuning, it is possible to distinguish RFI from true ETI signals by pointing the beams in diffe...

This paper compares the performance of several machine learning algorithms for the automatic categorization of corporate announcements in the Australian Stock Exchange (ASX) Signal G data stream. The article also describes some of the applications that the categorization of corporate announcements may enable. We have performed tests on two categorization tasks: market sensitivity, which indicat...

Aurintricarboxylic acid (ATA) is a potent inhibitor of many enzymes needed for cell and virus replication, such as polymerases, helicases, nucleases, and topoisomerases. This study examines how ATA interacts with the helicase encoded by the hepatitis C virus (HCV) and reveals that ATA interferes with both nucleic acid and ATP binding to the enzyme. We show that ATA directly binds HCV helicase t...