Abstract Background The advent of multi-detector computed tomographic pulmonary angiography has allowed better assessment the peripheral arteries, thereby increasing incidence embolism (PE). Even though most patients with PE are treated anticoagulation, its value in subsegmental setting (SSPE) not yet been confirmed. Purpose To perform a meta-analysis aimed at ascertaining extent to which antic...

Subacute sclerosing panencephalitis (SSPE) is a fatal, incurable, inflammatory, and neurodegenerative disease. The parieto-occipital lobes are the most frequently and severely affected. The basal ganglia, cerebellum, spinal cord and corpus callosum are less frequently involved [1-4]. Because magnetic resonance spectroscopy (MRS) provides information regarding in vivo brain metabolism and neuron...

Panencephalitis We read with great interest the recent contribution by Aydin et al in the February issue of the American Journal of Neuroradiology. They demonstrated gray matter volume reduction in the frontotemporal cortex of patients with subacute sclerosing panencephalitis (SSPE) without any apparent lesions on MR imaging. The authors achieved excellent results from their imaging assessment ...

In the realm of dementia, it is astonishing to note that neurofibrillary tangles (NFT) are microscopically identical in a childhood illness (SSPE) and in a dementia of late adult life (Alzheimer's disease). The words "Alzheimer-type" NFT in peer reviewed scientific articles written by acknowledged experts underscore the striking similarities in "tangles" in two different diseases. Subacute Scle...

Biken strain, a nonproductive measles viruslike agent isolated from a subacute sclerosing panencephalitis (SSPE) patient, contains a posttranscriptional defect affecting matrix (M) protein. A putative M protein was translated in vitro with RNA from Biken strain-infected cells. A similar protein was detected in vivo by an antiserum against a peptide synthesized from the cloned M gene of Edmonsto...

PURPOSE To evaluate the progression of CT and MR changes of the brain in subacute sclerosing panencephalitis (SSPE) as a basis for assessing the effects of different types of therapy. METHODS Fifty-two patients with SSPE were examined, 44 with MR imaging and 42 with CT of the brain on one or more occasions. A total of 92 MR and 67 CT studies were performed. RESULTS Correlation between the c...