نتایج جستجو برای: stacking sequence

تعداد نتایج: 418679  

2013
Dinesh Yadav Richard D. Sheardy

The human telomere sequence (TTAGGG)4 folds into an unusual conformation possessing three G-tetrads linked by TTA loops. The first loop is a propeller loop while the second and third loops are transverse loops. Using Circular Dichroism (CD) spectroscopy, we have investigated the effect of sequence context on the structures and stabilities of intramolecular G-quadruplexes related to the human te...

Journal: :Nucleic acids research 1998
L Cai L Chen S Raghavan R Ratliff R Moyzis A Rich

The cytosine-rich strand of the Tetrahymena telomere consists of multiple repeats of sequence d(AACCCC). We have solved the crystal structure of the crystalline repeat sequence at 2.5 A resolution. The adenines form two different and previously unknown clusters (A clusters) in orthogonal directions with their counterparts from other strands, each containing a total of eight adenines. The cluste...

Journal: :journal of physical & theoretical chemistry 2015
jumber kereselidze marine kvaraia george mikuchadze

the stacking mechanism of the 1h-4h proton transfer in 4-pyridone, 4-pyridinthione and p-aminopyridineare constructed. for quantitative description of this process by means of the quamtumchemicalmethod density functional theory (dft) the activation energy (

2009
Boian S. Alexandrov Vladimir Gelev Yevgeniya Monisova Ludmil B. Alexandrov Alan R. Bishop Kim Ø. Rasmussen Anny Usheva

No simple model exists that accurately describes the melting behavior and breathing dynamics of double-stranded DNA as a function of nucleotide sequence. This is especially true for homogenous and periodic DNA sequences, which exhibit large deviations in melting temperature from predictions made by additive thermodynamic contributions. Currently, no method exists for analysis of the DNA breathi...

Journal: :TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A 1999

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