Controlling the food-borne pathogen Listeria (L.) monocytogenes is of great importance from a food safety perspective, and thus for human health. The consequences of failures in this regard have been exemplified by recent large listeriosis outbreaks in the USA and Europe. It is thus particularly notable that tolerance to quaternary ammonium compounds such as benzalkonium chloride (BC) has been ...

Edible films can be used as carriers for antimicrobial compounds to assure food safety and quality; in addition, pathogenesis of food bacteria is related to a cell to cell communication mechanism called quorum sensing (QS). Oregano essential oil (OEO) has proved to be useful as food antimicrobial; however, its food applications can be compromised by the volatile character of its active constitu...

OBJECTIVES Quinolones accumulate in eukaryotic cells and show activity against a large array of intracellular organisms, but systematic studies aimed at examining their pharmacodynamic profile against intracellular bacteria are scarce. The present work aims at comparing intracellular-to-extracellular activities in this context. METHODS We assessed the activities of ciprofloxacin, levofloxacin...

Neutrophils are the most abundant leukocytes in circulation and provide a primary innate immune defense function against bacterial pathogens before development of a specific immune response. These specialized phagocytes are short lived (12-24 hours) and continuously replenished from bone marrow. We found that if the host is overwhelmed by a high inoculum of Listeria monocytogenes, neutrophils a...

Bacterial infections trigger the expression of type I and II interferon genes but little is known about their effect on type III interferon (IFN-λ) genes, whose products play important roles in epithelial innate immunity against viruses. Here, we studied the expression of IFN-λ genes in cultured human epithelial cells infected with different pathogenic bacteria and in the mouse placenta infecte...

The global spread of bacterial resistance to drugs used in therapy requires new potent and safe antimicrobial agents. DNA gyrases represent important targets in drug discovery. Schiff bases, thiazole, and triazole derivatives are considered key scaffolds in medicinal chemistry. Fifteen thiazolyl-triazole Schiff bases were evaluated for their antibacterial activity, measuring the growth inhibiti...

Cottage cheese is the largest segment of dairy market and most often consumed as a fresh food. The microbiological quality domestic cottage can pose problem for public health. belongs to group foods having potential health risk. aim this study was conduct research determine level sanitary safety types acquired from frequents markets Sarajevo Canton (Bosnia Herzegovina). Of total (n=40) analysed...

This study aimed to evaluate 50 different cheese samples in terms of certain microbiological parameters. The presence Salmonella spp. and Listeria cheeses were investigated by immunomagnetic separation conventional methods. Staphylococcus aureus was detected 4 samples, while 2 accepted suspicious 5/50 found positive with respect isolates determined as Proteus mirabilis. Therefore, not from the ...

herbs have been used for its medicinal properties from several thousand years ago. herbs, essences and extracts, possess a variety level of biological activities and antimicrobial activities of a large number of them have been proved. eucalyptus is one of these plants which the anti-virus effects of its extract has long been used to treat influenza and colds in most parts of the world. the aim ...