Experiments were conducted to evaluate the mo activity of aqueous leaf and stem-bark extract of Pe Euphorbiaceae) Lymnaea (Radix) acuminata (Lamar (Deshyas) – intermediate hosts of endemic schistosom cattle and livestock. The toxic effect of both extracts wa There was a significant negative correlation between observed, thus the LC10 values of P. tithymaloide leaf de 15.4 mg/L (96 h); LC50 decr...

BACKGROUND Many diseases are associated with oxidative stress caused by free radicals. Current research is directed towards finding naturally-occurring antioxidants of plant origin. The aim of the present study was to evaluate the in vitro antioxidant activities of Spondias pinnata stem bark extract. METHODS A 70% methanol extract of Spondias pinnata stem bark was studied in vitro for total a...

Stereospermum kunthianum, Cham Sandrine Petit (Bignoniaceae) known in English as pink jacaranda is used in traditional medicine to treat an array of ailments including febrile convulsions in infants and young children by the rural dwellers in Nigeria. This study examined the anticonvulsant activity of its aqueous stem bark extract (100 - 400mg/kg) against maximal electroshock and pentylenetetra...

BACKGROUND Herbal medicines have been in use for many years and remain widespread in developing countries; whereas, the use of complementary alternative medicine is on the increase in developed countries. Senna didymobotrya is important for its medicinal benefits among most communities in treating a wide range of ailments. MATERIALS AND METHODS Plants were collected from a cluster in Siaya, N...

The toxicity and mutagenic potential of most African plants implicated in the management of cancer have not been investigated. The ethanolic extracts of selected Nigerian plants were subsequently studied using the brine shrimp lethality tests, inhibition of telomerase activity and induction of chromosomal aberrations in vivo in rat lymphocytes. Morinda lucida root bark, Nymphaea lotus whole pla...

The safety of many African traditional herbal remedies is doubtful due to lack of standardization. This study therefore attempted to standardize two polyherbal formulations from Ogbomoso, Oyo State, Nigeria, with respect to the relative proportions (weight-for-weight) of their botanical constituents. Information supplied by 41 local herbal practitioners was statistically screened for consistenc...

Ficus dalhousiae Miq.(Family:Moraceae) known as Somalvalkam in Sanskrit is an endemic to peninsular India and very rare plant of Andhra Pradesh. It is found growing in rock crevices of dry deciduous forest. It is used in traditional system of Indian medicine in the treatment of liver disorders and cardiac problems Ficus species are rich source of flavonoids and polyphenolic compounds that are r...

Infection due to multidrug resistance pathogens is difficult to manage due to bacterial virulence factors and because of a relatively limited choice of antimicrobial agents. Thus, it is imperative to discover fresh antimicrobials or new practices that are effective for the treatment of infectious diseases caused by drug-resistant microorganisms. The objective of this experiment is to investigat...

BACKGROUND The paste of stem bark of Azadirachta indica (AI) has been traditionally used on wound and scar for rapid healing in Bundelkhand region of India. OBJECTIVE In the present investigation, wound healing potential of different extracts of stem bark of AI was explored in mice model. MATERIALS AND METHODS To study the wound healing properties in small animal model, the excision and inc...

Department of Biochemistry Federal University of Technology, Minna, Nigeria. Corresponding Author: Saidu, A.N ___________________________________________________________________________ Abstract The phytochemical screening and hypoglycemic effect of Carica papaya stem bark in alloxan-induced diabetic albino rats was investigated. Phytochemical analysis of the methanolic extract of Carica papaya...