Hereditary or familial hiperbilirubinemia comprises a group of syndromes (Dubin-Johnson’s, Rotor’s, hepatic storage disease) in which hyperbilirubinemia, predominantly unconjugated or conjugated, occurs as an isolated biochemical abnormality without evidence of either hepatocellular necrosis or cholestasis. We present a patient with Dubin-Johnson syndrome, one of the familial disorders associat...

X iv :p hy si cs /0 20 40 51 v1 [ ph ys ic s. op tic s] 1 7 A pr 2 00 2 Analysis of the ellipticity induced PMD and general scaling perturbation in a transmitting fiber. Maksim Skorobogatiy, Mihai Ibanescu, Steven Johnson, Ori Weisberg, Torkel Engeness, Steven Jacobs, Yoel Fink OmniGuide Communications, One Kendall Square, Build. 100, Cambridge, MA 02139, USA. [email protected] Abstract: Pr...

IBM Alumni (club members and non-members) who passed away in 2016: Henry 'Hank' Anderson, Elton Arneson, Michael Bjaastad, Thomas Budnick, Alan Calavano, William F. Carr, David C. Case, Scott Lynn Chambers, Arlene Christenson, James L. Clark, Joseph F. Cox, Steven Danek, Edna Denny, Lowell 'Ed' Dutton, Ambrose 'Bill' Ellis, Henry 'Hank' Eyrich, Harley Galen Flink, Michael Frain, Richard 'Dick' ...

To cite: Khoo ABS, Ali FR, Yiu ZZN, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016214926 DESCRIPTION A 36-year-old Sri Lankan man had a 10-year history of epilepsy, which was well controlled on sodium valproate. Having run out of his regular medication on vacation, he started taking his sister’s carbamazepine. He presented to the emergency department ...

Stevens-Johnson syndrome is an acute, inflammatory eruption of the skin and mucous membranes often associated with drug ingestion. A forty-five-year-old woman showed symptoms consistent with Stevens-Johnson syndrome two days after indapamide therapy was begun for the treatment of hypertension. Initial manifestations consisted of headaches, sore throat, cough, and symptoms of conjunctival inject...

The causes of Stevens-Johnson syndrome (SJS) can be categorized as iatrogenic, infectious or idiopathic. Drug-induced SJS is associated with various antibiotics, anticonvulsants, and other drugs. However, no previous reports have mentioned an association between chlordiazepoxide, a benzodiazepine sedative, and SJS. Here, we present a case of SJS induced by chlordiazepoxide overdose. This case r...

AIMS To understand the immunopathogenesis of the corneal conjunctivalisation in Stevens-Johnson syndrome. METHODS Conjunctivalised corneas from five patients with Stevens-Johnson syndrome were studied immunohistochemically for several cell surface antigens and two cytokines. Chemical injury specimens were also studied. RESULTS In all cases, immunohistochemistry revealed LFA-1, CD4, CD8, and...

El síndrome de piel escaldada estafilocócica, la escarlatina estafilocócica y el impétigo ampollar son patologías que tienen en común mecanismo lesión por toxinas exfoliativas producidas estafilococos, su presentación manifestaciones clínicas difíciles diferenciar otras sistémicas como enfermedad Kawasaki, Steven Johnson diferentes farmacodermias. En los últimos años se ha podido explicar molec...

Non-steroidal anti-inflammatory drugs are commonly prescribed in dental practice after minor oral surgical procedures such as tooth extraction. Diclofenac sodium is one of the non-steroidal antiinflammatory drugs widely used for pain relief in dentistry. Although adverse reactions to these drugs are rare, at times they can cause a life-threatening phenomenon. Stevens-Johnson syndrome is one suc...

OBJECTIVE To assess the type of severe skin reactions caused by valdecoxib treatment. DESIGN Case registry of severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. SETTING All hospitals in Germany that treat patients with severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. PATIENTS Five case notifications of Stevens-Johns...