This work was undertaken to contribute to the development of an epi-retinal prosthesis which may someday restore vision to patients blinded by outer retinal degenerations like retinitis pigmentosa. By stimulating surviving cells in tens or hundreds of distinct regions across the retinal surface, the prosthesis might convey the visual scene in the same way that images are represented on a comput...

Deep brain stimulation in the subthalamic nucleus is an effective and safe surgical procedure that has been shown to reduce the motor dysfunction of patients with advanced Parkinson's disease. Bilateral subthalamic nucleus deep brain stimulation, however, has been associated with declines in cognitive and cognitive-motor functioning. It has been hypothesized that spread of current to nonmotor a...

BACKGROUND Describe a rapid assessment for patients with idiopathic Parkinson's disease (PD) and deep brain stimulation of the subthalamic nucleus reporting worsening speech and/or gait problems. METHODS We retrospectively reviewed 29 patients that had improvement in gait and/or speech within 30 min after turning stimulation off. Clinical data analyzed include unified PD rating scale motor sc...

Chronic stimulation of the hypoglossus nerve may provide a new treatment modality for obstructive sleep apnoea (OSA). In previous studies we observed large differences in response to stimulation of the genioglossus (GG). We hypothesised that both individual patient characteristics and the area of the GG stimulated are responsible for these differences. In the present study, we compared the resp...

Approved: _______ Thesis Supervisor Physical Therapy and Rehabilitation Science __ Title and Department May 7, 2013____________________________ Date

In vitro application of pulsatile electrical stimulation to neonatal rat cardiomyocytes cultured on polymer scaffolds has been shown to improve the functional assembly of cells into contractile engineered cardiac tissues. However, to date, the conditions of electrical stimulation have not been optimized. We have systematically varied the electrode material, amplitude and frequency of stimulatio...

biophysical profile (bpp) test is the most commonly used antenatal test of fetal well-being. purpose of this study is determining the influence of acoustic stimulation (as) on bpp testing time. about 55 pregnant women at 35 to 42 weeks who referred to department of obstetric & gynecology at university of medical sciences, tabriz, iran, were selected randomly. we used abdominal ultrasound guidan...

Although low-threshold transcutaneous electrical nerve stimulation (TENS) is a modality used for control of pain, but its effect in the control of spasticity and change of excitability of a motor neuron is controversial. Therefore, this study was conducted to evaluate the effects of 15-min tripolar TENS of vertebral column and bipolar TENS of common peroneal nerve (300 µs width, 50 Hz) on synap...

OBJECTIVE To explore the effect of visual and haptic vertical stimulation on standing balance in post-stroke patients. METHODS Twenty-five post-stroke patients were recruited. We measured left/right standing pressure differences and the center of pressure (COP) parameters for each patient under three different conditions: no stimulation, visual, and haptic stimulated conditions. First, patien...

Invasive deep brain stimulation has proven to be clinically therapeutic for patients with drug-refractory epilepsy. The aim of this study was develop a novel transcranial electrical device as noninvasive modality seizure treatment. We fabricated and tested it in four swine brains depth electrodes surgically implanted under neuro-navigation. Stimulation two high-frequency alternating currents us...