Methods were devised for the selective alteration of parasympathetic control over the sinoatrial (SA) or the atrioventricular (AV) node in anesthetized, thoracotomized mongrel dogs. Two epicardial sites were located at which parasympathetic nerve fibers enroute to the SA or the AV node could be stimulated or blocked. Selective nerve stimulation was accomplished with brief pulses (0.05 msec), an...

promontory stimulation testing is both a valuable diagnosic tool and a crucial step in candidate selection for cochlear implantation. in this study we have compared the promontory stimulation test results between different subsets of patients with hearing loss in order to clarify the aspects of promontory stimulation which correlate best with the patients'characierisiics. patients with severe t...

postdate pregnancy is estimated to occur in 3% to 12% of all gestations. morbidity and mortality rates associated with this common obstetric problem are higher than those with term gestation. the incidence of fetal distress, birth injury, meconium aspiration, congenital malformations, macrosomia, and oligohydramnios is also greater in postdate pregnancies. we prospectively evaluated breast self...

Although low-threshold transcutaneous electrical nerve stimulation (TENS) is a modality used for control of pain, but its effect in the control of spasticity and change of excitability of a motor neuron is controversial. Therefore, this study was conducted to evaluate the effects of 15-min tripolar TENS of vertebral column and bipolar TENS of common peroneal nerve (300 µs width, 50 Hz) on synap...

Introduction: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects ...

Nervous systems are thought to encode information as patterns of electrical activity distributed sparsely through networks of neurons. These networks then process information by transforming one pattern of electrical activity into another. To store information as a pattern, a neural network must strengthen synapses between designated neurons so that activation of some of these neurons correspon...

Abstract Objective: To evaluate and compare the analgesic effects of caudal epidural administration of lidocaine (LIDO), caudal laser radiation and epidural lidocaine plus laser radiation in horses. Study design: A blinded, randomized, prospective, experimental cross-over study. Animals: Five healthy horses, 15.7 +/- 4.9 years of age, weighing 240 +/- 37 kg. Methods: The...

Intracortical microstimulation (ICMS) of a single site in the somatosensory cortex of rats and monkeys for 2-6 h increases the number of neurons responsive to the skin region corresponding to the ICMS-site receptive field (RF), with very little effect on the position and size of the ICMS-site RF, and the response evoked at the ICMS site by tactile stimulation. Large changes in RF topography are...

We have previously shown that the rat PCNA (proliferating cell nuclear antigen) gene promoter is responsive to serum stimulation. In this study, the sequence of the promoter responsive to serum stimulation has been localized in the region between nucleotides -70 and +125 relative to the transcription initiation site. This region contains an ATF site (nucleotides -51 to -44) and an AP-1 site (nu...

The highly convoluted and cytoarchitectonically diverse inferior frontal gyrus (IFG) of humans is known to be critically involved in a wide range of complex operations including speech and language processing. The neural circuitry that underlies these operations is not fully understood. We hypothesized that this neural circuitry includes functional connections within and between the three major...