Background. To identify, upon emergency department (ED) admission, predictors of unexpected death or unplanned intensive care/high dependency units (ICU/HDU) admission during the first 15 days of hospitalization on regular wards. Methods. Prospective cohort study in a medical-surgical adult ED in a teaching hospital, including consecutive patients hospitalized on regular wards after ED visit, a...

In occupational epidemiology, it is often possible to obtain repeated measurements of exposure from a sample of subjects (workers) who belong to exposure groups associated with different levels of exposure. Average exposures from a sample of workers can be assigned to all members of that group including those who are not sampled, leading to a group-based exposure assessment. We discuss how this...

Methods We analyse survival data reconstructed from two trials publications which reported extreme non-proportional hazards (with respective p-values as 9.19E-13 and 1.344E-24 in non-PH Grambsch-Thernau test). We use the Cox proportional hazards model, flexible parametric model and accelerated failure time model to estimate the time-independent hazard ratio, between-arm difference in restricted...

We present an asymptotic exponential bound for the deviation of the survival function estimator of the Cox model. We show that the bound holds even when the proportional hazards assumption does not hold.

The semi-parametric Cox proportional hazards (PH) regression model was developed by Sir David Cox (Cox 1972) and is by far the most popular model for survival analysis. The model defines a hazard function, which is the rate of an event occurring at any given time, given the observation is still at risk, as a function of the observed covariates. When data consist of independent and identically d...

tires represent a critical spare part in mines. there is a shortage of medium and large tires. in addition, with increased mining activities and the creation of new mines, the demand for tires has increased significantly. thus, it is particularly important for mining engineers to identify tire characteristics and correctly manage the spare part inventory. spare parts management is critical from...

For the final reduced multivariate Cox proportional hazards model presented in Table 3 of the main text, we assessed the proportional hazards assumption via the Schoenfeld residuals. We examined plots of the residuals for each variable against time to check for a non-­‐zero slope, which indicates that the proportional hazards assumption is violated (Hosmer et al. 1999). We then performed statis...