نتایج جستجو برای: stretched scar

تعداد نتایج: 20944  

Journal: :Biochemical Society Transactions 2013

Journal: :Physica A: Statistical Mechanics and its Applications 2007

Journal: :Physical Review Letters 2017

2012
Douwe M. Veltman Jason S. King Laura M. Machesky Robert H. Insall

Under normal conditions, the Arp2/3 complex activator SCAR/WAVE controls actin polymerization in pseudopods, whereas Wiskott-Aldrich syndrome protein (WASP) assembles actin at clathrin-coated pits. We show that, unexpectedly, Dictyostelium discoideum SCAR knockouts could still spread, migrate, and chemotax using pseudopods driven by the Arp2/3 complex. In the absence of SCAR, some WASP relocate...

Journal: :Circulation. Arrhythmia and electrophysiology 2013
Takeshi Sasaki Christopher F Miller Rozann Hansford Vadim Zipunnikov Menekhem M Zviman Joseph E Marine David Spragg Alan Cheng Harikrishna Tandri Sunil Sinha Aravindan Kolandaivelu Stefan L Zimmerman David A Bluemke Gordon F Tomaselli Ronald D Berger Henry R Halperin Hugh Calkins Saman Nazarian

BACKGROUND The association of local electrogram features with scar morphology and distribution in nonischemic cardiomyopathy has not been investigated. We aimed to quantify the association of scar on late gadolinium-enhanced cardiac magnetic resonance with local electrograms and ventricular tachycardia circuit sites in patients with nonischemic cardiomyopathy. METHODS AND RESULTS Fifteen pati...

2014
Suk Joon Oh Jihoon Yang Seon Gyu Kim Sung Won Jung Sung Hoon Koh

Scar revision is one of the fundamental techniques in the field of plastic and reconstructive surgery. Local flaps, such as a Z-plasty, W-plasty, or geometric broken-line closure, have been used for scar revision. Camouflaging a scar during scar revision for marginal scars from skin grafts and flaps, trapdoor scars, and linear scars is difficult. We describe our experience with the use of modif...

Journal: :Circulation. Arrhythmia and electrophysiology 2011
Paul A Scott John M Morgan Nicola Carroll David C Murday Paul R Roberts Charles R Peebles Stephen P Harden Nick P Curzen

BACKGROUND Characterization of sudden cardiac death (SCD) risk remains a challenge in the application of implantable cardioverter-defibrillator (ICD) therapy. Late gadolinium enhancement cardiac MRI (LGE-CMR) can accurately identify myocardial scar. We performed a retrospective, single-center observational study to evaluate the association between the extent and distribution of left ventricular...

2013
Bjorn Wieslander Katherine Wu Zak Loring Linus Andersson Terry Frank Gary Gerstenblith Gordon F Tomaselli Robert G Weiss Galen S Wagner Martin Ugander David G Strauss

INTRODUCTION Outcome of cardiac resynchronization therapy is severely worsened by myocardial scar at the left ventricular (LV) pacing site. We aimed to describe the diagnostic performance of electrocardiographic (ECG) criteria based on the Selvester QRS scoring system, first in localizing myocardial scar and second in screening for any non-septal scar in patients with strictly defined LBBB. M...

2002
Ryuichi Tatsumi Akihito Hattori Yoshihide Ikeuchi Judy E. Anderson Ronald E. Allen

Application of mechanical stretch to cultured adult rat muscle satellite cells results in release of hepatocyte growth factor (HGF) and accelerated entry into the cell cycle. Stretch-activation of cultured rat muscle satellite cells was observed only when medium pH was between 7.1 and 7.5, even though activation of satellite cells was accelerated by exogenous HGF over a pH range from 6.9 to 7.8...

18F-labeled fluoro-2-deoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) is an important imaging modality in the clinical workup of patients with chronic inflammatory disorders which present quite often with a fever of unknown origin. Sarcoidosis is a multisystem chronic inflammatory disorder with a wide clinical spectrum that can involve different organs. The diagno...

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