introduction pharmacologic treatment of radicular pain with oral medications is limited by adverse effects and concern for dependence. while topical formulations have been explored in pain research, there is no published literature evaluating the efficacy in radicular pain. we present the first three cases of radicular pain successfully treated with a topical formulation of diclofenac, ibuprofe...

keloids are aesthetically disfiguring and severely disabling. the optimal treatment remains undefined. this clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-fluorouracil on the prevention of keloids. in this double blind randomized clinical trial, fifty patients with keloids were randomly allocated in two groups. the control group were treated by periles...

conclusions although the results of this study showed superiority of application of emla cream as a topical anesthetic for pain relief of blood sampling, both lidocaine 5% and benzocaine 5% offer considerable efficacy in pain relief of venipuncture. results at the end of study, the emla products (a and b) caused a significant decrease in pain (p < 0.05) in comparison with the products c (lidoca...

in order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. the commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. the release of therapeutic agents in vitro from medicated sp...

Journal of the Geological Society Sri Lanka is a peer-reviewed and open access journal published by Lanka. It aims to publish most topical highest quality papers, summarizing results recent research across all sub-disciplines Earth Science. Papers are frequently interdisciplinary covering both pure applied fields Geology. Contributions often refer local, regional and/or international studies em...

Melatonin is an indoleamine derivative synthesised mainly in the pineal gland. Its association with periodontal disease and treatment exogenous supplementation of via oral route, topical application as local drug delivery has been documented evidences literature. This review article focuses on melatonin functions periodontium which includes its anti-inflammatory, antioxidant, antiresorptive imm...