Results: 51 patients underwent phacoemulsification under topical anesthesia and 49 patients underwent phacoemulsification under peribulbar anesthesia. No statistical differences were found in surgery duration, intra-operative complications, pain, blood pressure or Oxygen saturation (SPO2). Topical group did not require additional subconjunctival injection. 4/49 (8.16%) in peribulbar group requi...

HSV-2 is an important cause of the acute retinal necrosis (ARN) syndrome in younger patients. We describe an atypical case of HSV-2 ARN in the context of neonatal exposure and subconjunctival steroid injection. Clinicians should be aware of the association of neonatal or congenital exposure to HSV-2 as a risk factor for this disease because early treatment may improve outcome and/or avoid invol...

Although Staphylococcus aureus is an important cause of infectious diseases of the eye and hypersensitivity lesions of the cornea, little is known about ocular immunity to this pathogen. Using an enzyme-linked immunosorbent assay, we measured antibody titers to ribitol teichoic acid, the major antigenic determinant of S. aureus, in corneas as well as serum and tears after immunizing rabbits usi...

Two anticancer agents, one lipophilic, 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), and one hydrophilic, 5-(3,3-dimethyl-1-triazeno) imidazol-4-carboxamide (DTIC), were used to treat Brown-Pearce epithelioma in the anterior chamber of rabbit eyes. The BCNU test animals were divided into three groups: one treated by direct injection of the drug into the subconjuntival space or the anterior chamb...

PURPOSE To evaluate the short-term effects of a single subconjunctival injection of triamcinolone acetonide as an adjunct to subconjunctival bevacizumab for prevention of corneal neovascularization in rats. METHODS Chemical cauterization was performed in the central cornea of the right eye in 48 male Sprague-Dawley rats (4 eyes were excluded due to perforation and/or infection). Immediately a...

PURPOSES To evaluate the effect of subconjunctival bevacizumab in an experimental model of neovascularization in rabbit cornea. Determine its effect on vessels extension, inflammation, epithelialization of the cornea and whether the evaluation method used is appropriate to compare neovascular models. METHODS Experimental, prospective, randomized, blinded study in twenty rabbits subjected to c...

PURPOSE To assess the effect of single versus multiple subconjunctival ranibizumab injections in patients with an early pterygium recurrence. SETTING Single-center, academic practice. STUDY POPULATION Nine patients with early pterygium recurrence. OBSERVATIONAL PROCEDURE Subconjunctival ranibizumab (0.5 mg/0.05 mL) was administered adjacent to pterygium recurrence. Group 1 (n = 5) receive...