Evidence is presented that the proliferating gall bladder epithelium in the dog and guinea pig is capable of stimulating bone formation in certain connective tissues such as the abdominal wall. Other connective tissue areas such as the subepithelial connective tissue of the gall bladder and urinary bladder do not share in this tissue reaction and resist the bone stimulus of the epithelium. The ...

Lacking reliable data on cholesterol concentrations in muscle, adipose tissue, skin, and connective tissues (i.e., the "bulk tissues") in "normal" man, we have completed these analyses in 21 men and 8 women who died suddenly and unexpectedly; their ages ranged from 23 to 78 yr. In 11 of these subjects aged 20-40 yr, the mean cholesterol concentrations ranged from 180-440 mg/100 g dry tissue. In...

Introduction Several hundreds of cancer-producing chemical compounds are now known. By far the largest group, which contains all the very potent carcinogens, consists of compounds, mostly polycyclic aromatic hydrocarbons and simple derivatives of these, which give tumours at the site of application. Malignant tumours, resulting from prolonged contact of the tissues with the chemical compound, m...

BACKGROUND Mammals cannot regenerate the dermis and other skin structures after an injury and instead form a scar. However, a Xenopus laevis froglet can regenerate scarless skin, including the dermis and secretion glands, on the limbs and trunk after skin excision. Subcutaneous tissues in the limbs and trunk consist mostly of muscles. Although subcutaneous tissues beneath a skin injury appear d...

A second defining difference is the absence of pain and discomfort in metabolic fractures. Traumatic fractures, in contrast, are almost always extremely painful. This is easily explained. It is well known that bone has no pain fibers, while surrounding connective tissues are abundantly supplied with pain fibers. In metabolic fractures, which can take place with ordinary infant handling, surroun...

INTRODUCTION Knowledge of the nonlinear-elastic properties of soft tissues is essential for the development of reliable finite element models for biological systems. The compressive nonlinear-elastic properties of soft tissues are usually determined using unconfined compression tests. To determine the nonlinearelastic behavior of skin and subcutaneous tissues using a conventional approach, the ...