Introduction: 90% of the tumors in the head and neck are squamous-cell carcinomas (HNSCC), which have overall 5- year survival rate between 50% -60%. CD44 has been shown to be associated with the prognosis.  Materials and Methods: Biopsy specimens of 51 patients with oral tongue SCC were evaluated by Immunohistochemistry (IHC) for the CD44 antibody.  Results: There was no significant correlatio...

  Background and Objectives: Retinoblastoma is the most common intraocular pediatric malignancy. Angiogenic factor expression such as VEGF (vascular endothelial growth factor) in retinoblastoma can be confirmatory angiogenic potential of this tumor. This study was performed to determine the role of angiogenesis in local invasion of retinoblastoma and its correlation with patients’ sur...

Background: Plumbagin is as an important bioactive secondary metabolite found in the roots of Plumbago spp. The only one species, Plumbago europaea L., grows wild in Iran. The therapeutic use of plumbagin is limited due to its insufficient supply from the natural sources as the plants grow slowly and take several years to produce quality roots. O...

recently, reports have shown that gastric cancer has high abundance in iran and is at the second level in men, and fourth in total. this study aimed to determine the 5-year survival of gastric cancer patients and to investigate factors affecting the performance, based on tnm-7 staging system. in this study, we investigated 760 patients with gastric cancer since the beginning of 1993 to the end ...

the 5-year survival rate is a good prognostic indicator for patients with gastric cancer that is usually estimated based on kaplan-meier. in situations where censored observations are too many, this method produces biased estimations. this study aimed to compare estimations of kaplan-meier and weighted kaplan-meier as an alternative method to deal with the problem of heavy-censoring. data from ...

background: the study was developed in order to find a subset of potential factors, which affect birth distance pattern, regarding consideration on correlation of events of birth in a family and correlation within clusters/centers which other studies omit these correlations. methods: referring to documents that were registered for family in the health care centers on socio-economical zone, we c...

background: the oncologic behavior of mucinous adenocarcinoma (ma) of colorectal differs from non-mucinous adenocarcinoma (nma). ma is more advanced at diagnosis and has a poorer prognosis than nma. we aimed to evaluate prognostic factors and survival rate in patients with ma compared with nma in western iran. methods: during 2008-2015 in a retrospective study, 83 patients with crc referred to ...

background: primary gastric lymphoma (pgl) is an uncommon malignancy with various histological subtypes and treatment outcomes. the aim of this study was to investigate the potential prognostic factors and clinicopathological characteristics of iranian patients with pgl. methods: the clinicopathological characteristics of 60 patients with pgl were retrospectively reviewed from 2001 to 2012. the...