Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive form of peripheral (PTCL). It can present with signs symptoms that have broad differentials, including fevers, night sweats, skin rashes. In this case report, we an interesting young male Nigerian descent recently treated malaria who presented such picture was complicated, due to inconclusive excisional biopsy for lymphoma. He l...

OBJECTIVE To assess the effects of tibolone on climacteric symptoms, endometrium and serum lipid/lipoproteins in postmenopausal women receiving tamoxifen after surgery for breast cancer. DESIGN Double-blind, randomised, placebo-controlled, multicentre pilot study. SETTING Hospital outpatient clinic. SAMPLE Seventy postmenopausal women receiving tamoxifen following surgery for early breast...

A40-year-old man with no significant past medical history developed fever, dry cough, night sweats, chills, and malaise 1 week after hiking in the mountains in Michigan. He visited his primary care physician (PCP) and was treated with oral azithromycin for 5 days with no improvement. The patient then traveled to Europe for 2 weeks. During this trip, he had daily fevers, chills, cough, and sweat...

A community-based survey was conducted during 1995-1997 of factors related to menopausal and other symptoms in a multi-racial/ethnic sample of 16,065 women aged 40-55 years. Each of seven sites comprising the Study of Women's Health across the Nation (SWAN) surveyed one of four minority populations and a Caucasian population. The largest adjusted prevalence odds ratios for all symptoms, particu...

AIMS In breast cancer survivors, we aimed to describe the frequency of hot flashes and night sweats, frequency and type of treatment, and the association of hot flashes and use of calcium supplements. METHODS Charts of breast cancer survivors were reviewed for information about hot flashes, treatment for hot flashes, and calcium supplementation. Associations between variables were explored us...

BACKGROUND Behavioral strategies are recommended for menopausal symptoms, but little evidence exists regarding efficacy. PURPOSE Describe design and methodology of a randomized controlled 3 by 2 factorial trial of yoga, exercise and omega-3 fatty acids. METHODS Women from three geographic areas with a weekly average of ≥14 hot flashes/night sweats, who met exclusion/inclusion criteria, were...

Although most women report vasomotor symptoms (hot flashes, night sweats) during midlife, their etiology and risk factors are incompletely understood. Body fat is positively associated with vasomotor symptoms cross-sectionally, but the longitudinal relation between changes in body fat and vasomotor symptoms is uncharacterized. The study aim was to examine whether gains in body fat were related ...

OBJECTIVE This study was designed to assess endometrial histology in postmenopausal women not taking hormone replacement therapy, to evaluate side effects and efficacy of phytoestrogens in treating menopause-associated symptoms, and to determine whether 6 months of phytoestrogen supplementation altered endometrial histology. METHODS We performed a prospective, double-blinded, randomized, plac...

The randomized, double-blind, double-dummy, phase 3b RELIEF trial evaluated polycythaemia vera (PV)-related symptoms in patients who were well controlled with a stable dose of hydroxycarbamide (also termed hydroxyurea) but reported PV-related symptoms. Patients were randomized 1:1 to ruxolitinib 10 mg BID (n = 54) or hydroxycarbamide (prerandomization dose/schedule; n = 56); crossover to ruxoli...