The hippocampus frequently replays memories of past experiences during sharp-wave ripple (SWR) events. These events can represent spatial trajectories extending from the animal's current location to distant locations, suggesting a role in the evaluation of upcoming choices. While SWRs have been linked to learning and memory, the specific role of awake replay remains unclear. Here we show that t...

Place cell firing patterns reactivated during hippocampal sharp-wave ripples (SWRs) in rest or sleep are thought to induce synaptic plasticity and thereby promote the consolidation of recently encoded information. However, the capacity of reactivated spike trains to induce plasticity has not been directly tested. Here, we show that reactivated place cell firing patterns simultaneously recorded ...

Episodic and spatial memories each involve the encoding of complex associations in hippocampal neuronal circuits. Such memory traces could be stabilised from short- to long-term forms by consolidation processes involving the 'reactivation' of the original network firing patterns during sleep and rest. Waking experience can be replayed in many different brain areas, but an important role for the...

Polymer nanocomposites are being used more widely in a variety of industries. As the compatibilizer, Elvaloy-AC-3427 (EAC) was addition to Cloisite 30B (C3B) as reinforcement filler this research. For production Polyethylene/Cloisite 30B/Elvaloy AC-3427 nanomaterials, twin-screw extruder is employed. added Polyethylene matrix range 2%, 3%, 4%, and 5%. The mechanical thermal characteristics comp...

Abstract In recent years the use of organic matter soil amendments, such as agricultural by-products, has been implemented with aim increasing fertility, while minimizing environmental impact agriculture. Sheep wool residues (SWR) have shown beneficial effects on plant nutrition and properties, only few works assessed their microbial communities. The main this work was to investigate possible v...

In this paper, we present a unified framework for sensor validation, which is an extremely important module in the engine health management system. Our approach consists of several key ideas. First, we applied nonlinear minor component analysis (NLMCA) to capture the analytical redundancy between sensors. The obtained NLMCA model is data driven, does not require faulty data, and only utilizes s...

Cortico-hippocampal interactions during sleep are believed to reorganize neural circuits in support of memory consolidation. However, spike-timing relationships across cortico-hippocampal networks-key determinants of synaptic changes-are poorly understood. Here we show that cells in prefrontal cortex fire consistently within 100 ms after hippocampal cells in naturally sleeping animals. This pro...

Vestibular dysfunction is a frequent clinical problem, leading to dizziness and imbalance. Genes play an important role in its etiology, but the genetics are complex and poorly understood. In this study we have analyzed the complex inheritance pattern in the Epistatic circler mouse, which shows circling behavior indicative of vestibular dysfunction in the mouse. This phenotype exists in a propo...