The in situ regeneration of reduced nicotinamide cofactors (NAD(P)H) is necessary for practical synthesis of many important chemicals. Here, we report the engineering of a highly stable and active mutant phosphite dehydrogenase (12x-A176R PTDH) from Pseudomonas stutzeri and evaluation of its potential as an effective NADPH regeneration system in an enzyme membrane reactor. Two practically impor...

The tripeptide Z-GlyPheLeuNH2 was continuously synthesized in a high yield from three amino acid derivatives, Z-Gly, PheOMe, and LeuNH2, by immobilized thermolysin (IMT) and immobilized alpha-chymotrypsin (IMC) in an organic solvent, ethyl acetate. The optimal conditions for the synthesis of Z-GlyPheOMe were established theoretically. The yield of Z-GlyPheOMe with IMT in ethyl acetate saturated...

The development of controlled synthesis protocols of nanostructured materials with tailored particle size and shape has been a significant research area in nanoscience and nanotechnology. Much innovative research efforts had been focused on finding suitable chemical reagents and synthetic methodologies that offer opportunities to produce the desired structure-function controlled nanomaterials. ...

Immobilized whole cells of Rhodotorula rubra MIM147 were used in a packed bed flow reactor for the enantioselective reduction ?-ketonitriles and obtainment key building block synthesis antidepressant drug duloxetine.

The effect of several operating parameters on the kinetics synthesis peroxyester tert -butyl peroxy-2-ethylhexanoate was investigated in detail using a capillary microreactor and reactor model developed.

A novel approach for the investigation of reaction kinetics using a polytropic miniplant reactor featuring highly resolved fibre optic temperature measurement and FTIR gas phase analysis is presented methanol synthesis.

Abstract Systematic experimental data have been obtained on the results of catalytic chemical reactions in a microchannel reactor for synthesis methanol from gas. Synthesis gas contains hydrogen, carbon monoxide and dioxide, as well nitrogen ratio 58/29/5/8. The experiments were carried out at different flow rates temperature range 190-260C. Experiments also fixed bed pressures.