P a t i e n t s 335 of 573 patients (median age 35 y, 61% women) who had Crohn disease ≥ 3 months in duration; had a Crohn’s Disease Activity Index (CDAI) score between 220 and 400; and responded to a single infusion of infliximab, 5 mg/kg, within 2 weeks. Response was defined as a decrease in CDAI score ≥ 70 points from baseline and a reduction in the total score ≥ 25%. Exclusion criteria incl...

From March 2008 through February 2014, 80 patients aged 1-95 years (43 men and 37 women) were diagnosed with tinea faciei by a rural Japanese clinic. The affected sites were the cheek in 42 patients (52.5%), the auricles and area surrounding the auricles in 16 (20.0%), and the mandible in 12 (15.0%); 33 patients (41.2%) had concurrent ringworm in areas other than the face. Twenty-one patients (...

OBJECTIVE Androgen deprivation therapy (ADT) puts patients at an increased risk of developing osteoporosis. Assessment of bone mineral density (BMD) is most commonly performed by dual energy X-ray absorptiometry (DXA). Alternative ways of estimating BMD, such as quantitative ultrasound (QUS) measurement of the heel, are explored as DXA is expensive, non-portable and uses ionising radiation. We ...

BACKGROUND Matrix Gla protein (MGP) is an important inhibitor of calcification. The objective of the present study of patients with type 2 diabetes and normal or slightly altered kidney function was to evaluate levels of inactive, dephospho-uncarboxylated MGP(dp-ucMGP) and total uncarboxylated MGP(t-ucMGP) and assess their links with biological and clinical parameters (including peripheral vasc...

Background Immunoglobulin A nephropathy (IgAN) is one of the leading causes end-stage kidney disease (ESKD). Many studies have shown significance pathological manifestations in predicting outcome patients with IgAN, especially T -score Oxford classification. Evaluating prognosis may be hampered without renal biopsy. Methods baseline dataset 690 IgAN and an independent follow-up 1,168 were used ...

This paper presents a cross-sectional study testing whether dolphins that are born in aquarium pools where they hear trainers' whistles develop whistles that are less frequency modulated than those of wild dolphins. Ten pairs of captive and wild dolphins were matched for age and sex. Twenty whistles were sampled from each dolphin. Several traditional acoustic features (total duration, duration ...

BACKGROUND Asthma is the most common, chronic, childhood disease. Its chronic nature and long-term treatment decrease the quality of life of children and significantly affect the family function. This study was conducted to assess the impact of family empowerment on the quality of life of school-aged children with asthma. MATERIALS AND METHODS This was a quasi-experimental study. Forty-five a...