The objective of this study was to assess the transdermal delivery of drugs using iontophoresis with cation- and anion-exchange fibers as controlled drug delivery vehicles. Complexation of charged model drugs with the ion-exchange fibers was studied as a method to achieve controlled transdermal drug delivery. Drug release from the cation-exchange fiber into a physiological saline was dependent ...

Raphanus sativus (Cruciferaceae), commonly known as radish is widely available throughout the world. From antiquity it has been used in folk medicine as a natural drug against many toxicants. The present study was designed to evaluate the hepatoprotective activity of radish (Raphanus sativus) enzyme extract (REE) in vitro and in vivo test. The IC50 values of REE in human liver derived HepG2 cel...

One of the most intriguing aspects of hypnosis has been its ability to produce, ia the best Ss, very unusual subjective experiences. In the past decade these phenomena have been largely overlooked, as the emphasis in hypnosis research has been on the development of objective measures of suggestibility (Shor & Orne, 1962; Weitzenhoffer & Hilgard, 1959; 1962; 1963), the nature of hypnotic suggest...

Surface tension is probably one of the most difficult phenomena to measure. Although a great deal of ingenuity has been spent for almost a century in devising accurate techniques, the figures obtained deviate more from each other for the same substance, according to different authors, than any other constant characterizing the substance. I t is well ,known tha t the two classes of methods of me...

Alzheimer's disease (AD) is a multifactorial disorder with several target proteins contributing to its etiology. In search for multifunctional anti-AD drug candidates, taking into account that the acetylcholinesterase (AChE) and beta-amyloid (Aβ) aggregation are particularly important targets for inhibition, the tacrine and benzothiazole (BTA) moieties were conjugated with suitable linkers in a...

We proposed the telep esence method tha enables u to ins antly look around a visualized spa e of a dynamic real world. How ve , it was a problem wi h the conven ional omnidirectional camera with a NTSC camera and a hyperboloidal mirror tha the re olution was poor. This paper desc ibes a new telep e n e system with an omnidirectional HD camera, which us d a HD camera and a hyperboloidal mi or. T...