The glutathione S-transferase mu 2 gene (GSTM2) encodes a GST functioning in the elimination of electrophilic compounds and the regulation of cell growth. In this study, the sequence of porcine GSTM2 gene that contains the complete sequence encoding a protein of 218 amino acids was cloned. The deduced amino acid sequence shared 76%, 78% and 76% identity with that of human, mouse and rat, respec...

We extend Dechow and Dichev’s [2002] model of current accruals quality (CAQ) to consider total accruals quality (TAQ). While the two measures are conceptually similar (both reflect the standard deviation of the residuals from the mapping of accruals into lead and lag cash flows), they differ in terms of the definitions of accruals and cash flows as well as the number of lead and lag cash flow t...

BACKGROUND & OBJECTIVE Cholesteryl ester transfer protein (CETP) gene polymorphism is known to be associated with changes in lipid profiles. Primary hyperlipidaemia is considered to be a major risk factor for pancreatitis, atherosclerosis and coronary heart disease. We investigated the association of one common polymorphism in the CETP gene (Taq1B) with plasma lipid levels and CETP activity in ...

We investigated the association of developmental dysplasia of the hip (DDH) and primary protrusion acetabuli (PPA) with Vitamin D receptor polymorphisms Taq I and Fok I and oestrogen receptor polymorphisms Pvu II and Xba I. 45 patients with DDH and 20 patients with PPA were included in the study. Healthy controls (n = 101) aged 18–60 years were recruited from the same geographical area. The con...

Thermus aquaticus (Taq) DNA polymerase was used to measure the extension efficiency for all configurations of matched and mismatched base pairs at template-primer 3'-termini. The transition mispairs, A(primer).C, C.A, G.T, and T.G were extended 10(-3) to 10(-4)-fold less efficiently than their correctly paired counterparts. Relative efficiencies for extending transversion mispairs were 10(-4) t...

About 75% of patients with newly diagnosed chronic phase (CP) chronic myeloid leukemia (CML) treated initially with imatinib achieve complete cytogenetic remission (CCyR),1 and imatinib also induces Ph negativity, though less often, in patients treated in advanced phases of CML. Patients in CCyR may however still have as many as 1010 leukemia cells in their body,2 and in CML the quantity of suc...

2.Cusi, M.G., M. Valassina and P.E. Valensin. 1994. Comparison of M-MLV reverse transcriptase and Tth polymerase activity in RTPCR of samples with low virus burden. BioTechniques 17:1034-1036. 3.Fiorenza, M.T. and F. Mangia. 1998. Quantitative RT-PCR amplification of RNA in single mouse oocytes and preimplantation embryos. BioTechniques 24:618-623. 4.Huang, Z., M.J. Fasco and L.S. Kaminsky. 199...

We demonstrate that despite lacking a 3'----5' proofreading exonuclease, the Thermus aquaticus (Taq) DNA polymerase can catalyze highly accurate DNA synthesis in vitro. Under defined reaction conditions, the error rate per nucleotide polymerized at 70 degrees C can be as low as 10(-5) for base substitution errors and 10(-6) for frameshift errors. The frequency of mutations produced during a sin...

This study examines various measures of trading costs estimated from highfrequency (TAQ) data and the extent to which these measures can be estimated from daily data (CRSP). The high-frequency measures tend to be positively correlated. Posted spreads and effective costs are very highly correlated. Price impact measures and other statistics derived from dynamic models, however, are only modestly...