نتایج جستجو برای: tear osmolarity

تعداد نتایج: 13210  

2016
Anastasios John Kanellopoulos George Asimellis

Dry eye is a multifactorial, progressive, and chronic disease of the tears and ocular surface. The disease is multi-factorial and has intermittent symptoms. Discomfort, visual disturbance, tear film instability with potential damage to the ocular surface, and increased tear film osmolarity are known associates. Dry eye is a common clinical problem for eye-care providers worldwide and there is a...

Journal: :Heliyon 2023

PurposeTo evaluate patterns and opinion from international experts with respect to dry eye disease (DED) diagnosis in clinical practice.MethodsAn online survey was distributed worldwide DED experts. The use of tests evaluated including: symptoms questionnaires, functional tests, tear stability, volume, composition, surface damage inflammation, eyelid assessment. After the subjective importance ...

Journal: :Investigative ophthalmology & visual science 2015
Laura Elizabeth Downie

PURPOSE To assess the diagnostic performance of a novel, automated, noninvasive measure of tear film stability derived from Placido disc videokeratography, the tear film surface quality breakup time (TFSQ-BUT), as a clinical marker for diagnosing dry eye disease (DED) relative to a standard of tear hyperosmolarity. METHODS This prospective, cross-sectional study involved 45 participants (28 D...

2014
Vladimir Vsevolodovich Brjesky Yury Fedorovich Maychuk Alexey Vladimirovich Petrayevsky Peter Gerrievich Nagorsky

Artificial tear preparations are important in the management of dry eye syndrome. We present the findings from four recently published studies conducted in Russia assessing Hylabak(®) (marketed as Hyabak(®) in Europe), a preservative-free hyaluronic acid preparation, for the treatment of dry eye syndrome. All studies had an open, noncomparative design, but one compared the findings with those f...

Paper-based microfluidic system for tear electrolyte analysis† †We declare no competing financial interests. ‡ ‡Electronic supplementary information (ESI) available: Microscopic images of G1 paper and G41 paper under brightfield; optimization of CO2 laser radiation fluence and beam speed for ablating filter paper-G1; photographs of DI water diffusion in microfluidic channels with different lengths, different widths, different viscosities of fluid and different numbers of channels; fluorescence intensity readouts of Na+ and K+ ions with varied concentrations of fluorescent probes; effect of variations in temperature on fluorescence intensity; photographs of DMSO on G1 paper dried in the air; calibration curves of electrolyte sensing on G1 paper using microplate reader measurement; calculation of sensitivity of the fluorescent sensors based on International Union of Pure and Applied Chemistry (IUPAC) guidelines; quantification of ion interference in buffer solution and artificial tear fluid; light attenuation of LED lights using different optical filters; the design of the sample collection device and its potential clinical use; calibration curves of electrolyte sensors using the paper-based microfluidic system; quantifications of evaporation effect on sampling process; design of the sample collection device and its potential clinical use; batch-to-batch variation experiments; equation for background subtraction; movies of sample collection and measurements. See DOI: 10.1039/c6lc01450j Click here for additional data file. Click here for additional data file. Click here for additional data file. Click here for additional data file.

2017
Ali K Yetisen Nan Jiang Ali Tamayol Guillermo U Ruiz-Esparza Yu Shrike Zhang Sofía Medina-Pando Aditi Gupta James S Wolffsohn Haider Butt Ali Khademhosseini Seok-Hyun Yun

The analysis of tear constituents at point-of-care settings has a potential for early diagnosis of ocular disorders such as dry eye disease, low-cost screening, and surveillance of at-risk subjects. However, current minimally-invasive rapid tear analysis systems for point-of-care settings have been limited to assessment of osmolarity or inflammatory markers and cannot differentiate between dry ...

2015
Deanne L. Nicholas Wayne D.H. Gillan

http://www.avehjournal.org doi:10.4102/aveh.v74i1.12 The meibomian glands of the upper and lower eyelids play a valuable role in secreting the lipid layer of the tear film. Disturbances in meibomian gland function may result in altered secretion and variations in tear composition which may lead to meibomian gland dysfunction and evaporative dry eye, leading to ocular discomfort. To diagnose and...

2017
Ali K. Yetisen Nan Jiang Ali Tamayol Guillermo U. Ruiz-Esparza Yu Shrike Zhang Sofía Medina-Pando Aditi Gupta James S. Wolffsohn Haider Butt Ali Khademhosseini Seok-Hyun Yun

The analysis of tear constituents at point-of-care settings has a potential for early diagnosis of ocular disorders such as dry eye disease, low-cost screening, and surveillance of at-risk subjects. However, current minimally-invasive rapid tear analysis systems for point-of-care settings have been limited to assessment of osmolarity or inflammatory markers and cannot differentiate between dry ...

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