Recent experimental studies suggest that the use of suture anchors for rotator cuff tear (RCT) repair transfers the "weak link" to the suture-tendon interface where failure occurs as the sutures cut through the tendon. The purpose of this study was to evaluate the effect of using a suture augmentation button on the fixation strength of rotator cuff tendon repair. A 1.5 cm by 2 cm defect was cre...

BACKGROUND Tears of the rotator cuff are one of the most common tendon disorders. Treatment often includes surgical repair, but the rate of failure to gain or maintain healing has been reported to be as high as 94%. This has been substantially attributed to the inadequate capacity of tendon to heal once damaged, particularly to bone at the enthesis. A number of strategies have been developed to...

INTRODUCTION Rotator cuff tears of the shoulder are a common cause of pain and disability and surgical repair of these injuries is plagued with recurrent tear rates ranging from 20-70% [1]. The time from onset of injury to time of surgical repair is one important factor in repair outcome [2]. Animal models have recently been developed to address hypotheses related to rotator cuff tendon to bone...

Abstract Aim Recurrent tears after surgical tendon repair remain common, with 40% of rotator cuff repairs failing within one year. Repair failures can be partly attributed to the use sutures not designed for cellular niche. Synthetic electrospun materials mechanically support while providing topographical cues that modulate immune response promote wound healing. Here, a novel suture made from t...

Different tendons are designed to withstand different mechanical loads in their individual environments. Variable physiologic loading ranges and correspondingly different injury thresholds lead to tendon heterogeneity. Also, tendon heterogeneity is evident when examining how different tendons regulate their response to changes in mechanical loading (over- and under-loading). The response of ten...

Stem cells have been widely used in tendon tissue engineering. The lack of refined and controlled differentiation strategy hampers the tendon repair and regeneration. This study aimed to find new effective differentiation factors for stepwise tenogenic differentiation. By microarray screening, the transcript factor Fos was found to be expressed in significantly higher amounts in postnatal Achil...

OBJECTIVE To assess the potential of adipose-derived nucleated cell (ADNC) fractions to improve tendon repair in horses with collagenase-induced tendinitis. ANIMALS 8 horses. PROCEDURES Collagenase was used to induce tendinitis in the superficial digital flexor tendon of 1 forelimb in each horse. Four horses were treated by injection of autogenous ADNC fractions, and 4 control horses were i...

In the rare cases with serious damage of the Medial Collateral Ligament (MCL) of the knee requiring surgical treatment, ligament remnants may be inadequate for a good repair. In such cases, reconstruction should be performed and technical options may be limited. We used an Achilles tendon allograft and applied it using the Pulvertaft weave technique for tendon repair. We found no previous repor...

PURPOSE The side-to-side (SS) tendon suture technique was designed to function as a repair that permits immediate postoperative activation and mobilization of a transferred muscle. This study was designed to test the strength and stiffness of the SS technique against a variation of the Pulvertaft (PT) repair technique. METHODS Flexor digitorum superficialis (FDS) and flexor digitorum profundu...

Existing literature has not explored repeated tendon ruptures caused by torn intratendinous ganglions. The treatment of ganglion the hand remains a challenge, as it is difficult to completely excise while also preserving tendon. Herein report on case ruptured in extensor digitorum communis which resulted reconstruction surgeries. authors incorporated an acellular dermal matrix with transfer, de...