BACKGROUND The low uptake of tetanus vaccine and its resultant high burden of tetanus in Nigeria suggest the need to improve routine and booster vaccination in children and adolescents. However, epidemiological evidence for vaccination in the adolescent age group needed for effective strategy and policy formulation is lacking. This study was carried out to determine the prevalence of protective...

Tetanus is a vaccine-preventable disease and remains an important cause of under five morbidity and mortality, especially in the developing countries. Tetanus is considered as a failure of public health system. Here the clinical course of neonatal tetanus of eighteen days old female baby who was presented to Daror health centre with complaints of refusal to take feeding, inability to open her m...

Protection to tetanus is often not optimal in developing countries due to incomplete vaccination schemes, or decreased efficacy of vaccination. In this study we investigated the immunological response to tetanus booster vaccination in school children living in a semi-urban or in a rural area of Gabon. Tetanus-specific total IgG as well as antibody subclasses of the IgG1, IgG2, IgG3 and IgG4 iso...

PURPOSE Patients with beta thalassemia major are at increased risk for bacterial infections specially splenectomized patients. The aim of this study was to determine the anti-tetanus antibody concentration among patients with beta thalassemia major. MATERIALS AND METHODS The anti-tetanus antibody concentration was investigated in 224 patients with thalassemia major and 224 healthy subjects ma...

The simultaneous administration of B.C.G. vaccine, diphtheria-tetanus toxoid aluminium hydroxide adsorbed vaccine, and oral poliovaccine was studied in 628 children aged 13-14 years between 1966 and 1969 in Newham, London. The efficacy of these vaccines was unaffected by administering them at the same time; routine simultaneous administration is considered justified when organizational difficul...

BACKGROUND In spite of the clear-cut guidelines regarding tetanus immunization, we have observed that tetanus toxoid injection is often given after injury without considering previous immunization status. One of the reasons for this could be that the doctors themselves are not aware of the correct immunization schedules against tetanus. AIMS 1. To assess the knowledge about tetanus immunizati...

Sir, I thought your readers may be interested in the management of a recent case of tetanus which occurred at this hospital. A 63-year-old lady presented to the Accident and Emergency Department soon after laceration to her right leg, caused by a sheet of glass taken from a dismantled greenhouse in her garden. A 'V'-shaped flap, 4 cm each limb, an apparently clean and subcutaneous wound, was si...

The primary objective of this study was to assess determinants of vaccine uptake in adults living in Germany exemplified by one standard vaccination (tetanus) and one vaccination targeting specific risk-groups (seasonal influenza). Data from 21,262 telephone household-interviews representative of the adult population in Germany were collected in 2009 and analysed. A total 73.1% of the adult pop...

Tetanus is a medical condition characterized by a prolonged contraction of skeletal muscle fibersTetanospasmin is a neurotoxin which causes the symptoms of tetanus.It is a neurotoxin produced by gram positive bacterium Clostridium tetani.infection starts with wound contamination and steadily progresses causing muscle spasms known as “lock jaw Under the present study, all cases of tetanus admitt...

INTRODUCTION Tetanus is a severe and potentially fatal infection caused by the bacterium Clostridium tetani. Of all the cases described in literature, generalized tetanus is by far the most common presentation, but it may also present as neonatal tetanus, cephalic tetanus, and localized tetanus, the latter two being much rarer. In this case report, we present the rare form of this disease, i.e....