A new type of nucleic acid analogues with a phosphoryl guanidine group is described. Oxidation of polymer-supported dinucleoside 2-cyanoethyl phosphite by iodine in the presence of 1,1,3,3-tetramethyl guanidine yields a dinucleotide with an internucleoside tetramethyl phosphoryl guanidine (Tmg) group as the main product. The Tmg group is stable under conditions of solid-phase DNA synthesis and ...

The magnetic properties of the two isostructural molecule-based magnets, Ni(NCS)$_{2}$(thiourea)$_{2}$, $S$ = 1, [thiourea SC(NH$_2$)$_2$] and Co(NCS)$_{2}$(thiourea)$_{2}$, 3/2, are characterised using several techniques in order to rationalise their relationship with structural parameters ascertain changes caused by substitution spin. Zero-field heat capacity muon-spin relaxation measurements...

some n¬-acyl-n'-aryl thiourea derivatives 4(a-f) have been prepared by the reaction of acyl halides ammonium thiocyanate and aryl amines. the structures of synthesized compounds have been characterized by ir, 1hnmr spectral studies. the synthesized compounds 5(a-f) have been screened for antibacterial activity. the effect of the structure of the investigated compounds on the antibacterial ...

a theoretical density functional theory (dft) study was performed on a series of the neutral n-phenylthiourea substituents (p-oc2h5, p-ch3, m-ch3, h, p-cl, p-br, m-cl, and p-no2) as the sensor of acetate and fluoride anions. the hydrogen bond character was analyzed as a scale of the sensing activity. it was confirmed that hydrogen bond between the p-no2 derivatives of n-phenylthiourea and fluor...

L-alanine cadmium chloride (LACC) crystals doped with thiourea were grown by slow evaporation technique. The solubility of the samples were determined gravimetrically at various temperatures in the range 30 50 o C. Single crystals of thiourea doped L-alanine cadmium chloride were tested for the crystal structure by single crystal XRD studies. The values of SHG efficiency and laser damage thresh...

The glycosylation of O-glycosyl trichloroacetimidate donors using a synergistic catalytic system of electron-deficient pyridinium salts/aryl thiourea derivatives at room temperature is demonstrated. The acidity of the adduct formed by the 1,2-addition of alcohol to the electron-deficient pyridinium salt is increased in the presence of an aryl thiourea derivative as an hydrogen-bonding cocatalys...

A Simple and convenient protocol is described for preparation of some new 5-(2’hydroxy-3’,5’-dichlorophenyl)-4-(4’-chlorobenzyl)-2-amino-1,3-thiazole and 5-(2’hydroxy-3’,5’-dichlorophenyl)-4-(4’-chlorobenzyl)-2-aminophenyl-1,3-thiazole, were synthesized by refluxing dibrominated chalcone with thiourea or N-phenyl thiourea in good yields. The newly synthesized titled compounds were screened for ...

Earlier studies have shown that it is possible to induce a mitotic wave in the livers of rats by three consecutive intraperitoneal injections of large doses of thiourea (14). A subsequent study was undertaken to observe the effect on the liver of prolonged treatment with thiourea. No changes were found after such treatment. However, in five out of six rats which survived for more than 1 year, m...