Photochemistry provides a wide range of alternative reagents that hold potential for use in bimolecular functionalisation proteins. Here, we report the synthesis and characterisation metal ion binding chelates derivatised with disubstituted tetrazoles photoradiochemical labelling monoclonal antibodies (mAbs). The photophysical properties featuring extended aromatic systems auxochromic substitue...

Novel scaffolds are of uttermost importance for the discovery of functional material. Three different heterocyclic scaffolds easily accessible from isocyanoacetaldehyde dimethylacetal 1 by multicomponent reaction (MCR) are described. They can be efficiently synthesized by a Ugi tetrazole multicomponent reaction of 1. We discuss the synthesis, 3D structures, and other physicochemical properties.

The coordination of 2-pyridyltetrazolate and ortho-xylene-linked bis(NHC)cyclophane to Pt(II) yielded a novel complex characterised by enhanced pure deep-blue emission, whose intensity can be modulated via methylation of the tetrazole ring.

We report a chemical lipidation model for the study of protein lipidations in vitro and in live mammalian cells based on a bioorthogonal, photoinduced tetrazole-alkene cycloaddition reaction.

An adaptive tetrazole-derived host provides insight into tetrazolate-biomolecule interactions, and is the first member of a new family of receptors that function in pure water.

Highly purified 5-vinyl-1H-tetrazole was synthesized, which is in great demand modern medicine and industry as a monomer for obtaining nitrogen-rich macromolecular compounds reagent the complete synthesis of biological compounds. The molecular structure studied experimentally with sequential X-ray diffraction analysis theoretically ab initio quantum chemical calculations. data from differential...

With the critical increase in patients suffering from various types of malignant growth, it is obvious that quick steps development novel and viable agents should be taken. In current study, we focused on a synthetic approach for synthesis tetrazole derivatives using Ugi-4CR by employing gold catalyst water: methanol media. Gold’s adjustable nature, unique characteristics, mild reaction conditi...