The theory of one-step rewriting for a given rewrite system R and signature is the rst-order theory of the following structure: its universe consists of all-ground terms, and its only predicate is the relation \x rewrites to y in one step by R". The structure contains no function symbols and no equality. We show that there is no algorithm deciding the 9 8-fragment of this theory for an arbitrar...

Brain regions typically contain intermixed subpopulations of neurons with different connectivity and neurotransmitters. This complicates identification of neuronal phenotypes in electrophysiological experiments without using direct detection of unique molecular markers. A prime example of this difficulty is the identification of dopamine (DA) neurons in the midbrain ventral tegmental area (VTA)...

The production of potentially pathogenic anti-DNA autoantibodies in SLE is driven by special, autoimmune T helper (Th) cells. Herein, we sequenced the T cell receptor (TCR) alpha and beta chain genes expressed by 42 autoimmune Th lines from lupus patients that were mostly CD4+ and represented the strongest inducers of such autoantibodies. These autoimmune TCRs displayed a recurrent motif of hig...

Recent research on Therapeutic Hypothermia (TH) post cardiac arrest has raised questions about its implementation and benefits. TH to 32-34 degrees C is still included in international guidelines for post-cardiac arrest care. We investigated how Irish ICUs are utilising TH as part of their management of patients post cardiac arrest using a telephone survey of all Irish ICUs. All 25 ICUs in Irel...

The U-Th radioactive disequilibrium measurements with Multi-Collector Inductively Coupled Plasma Mass Spectrometry (MC-ICP-MS) were applied to a coral reference; JCp-1 distributed by the Geological Survey of Japan to evaluate homogeneity of the standard material. The two times of standard deviations (2SDs) of [U/U]isotope ratio, [ U/U]isotope ratio, U abundance, [ 230Th/ Th]isotope ratio, and T...

We review recent results on solitons in supersymmetric (SUSY) non-Abelian gauge theories, focusing on our papers: hep-th/0405194, hep-th/0405161, and hep-th/0404198. We construct the BPS multi-wall solutions in supersymmetric U(NC) gauge theories in five dimensions with NF(> NC) hypermultiplets in the fundamental representation. Exact solutions are obtained with full generic moduli for infinite...

BACKGROUND Evidences suggest that β3 -adrenoceptor (β3-AR) plays an important role in heart failure (HF), although no data is reported indicating how these effects may change with the increasing age. Pulmonary congestion and edema are the major life-threatening complications associated with HF. The purpose of this study is to explore the relationship between the anti-β3-AR autoantibody and the ...

Background—Therapeutic hypothermia (TH) improves survival and confers neuroprotection in out-of-hospital cardiac arrest (OHCA), but TH is underutilized, and regional systems of care for OHCA that include TH are needed. Methods and Results—The Cool It protocol has established TH as the standard of care for OHCA across a regional network of hospitals transferring patients to a central TH-capable ...

Thyroid hormone (TH) signaling components are expressed during retinal development in dynamic spatial and temporal patterns. To probe the competence of retinal cells to mount a transcriptional response to TH, reporters that included thyroid response elements (TREs) were introduced into developing retinal tissue. The TREs were placed upstream of a minimal TATA-box and two reporter genes, green f...

We sought to determine the source of the signal(s) that promotes expression of the catecholamine (CA) enzyme tyrosine hydroxylase (TH) in cultured neurons of embryonic rat cerebral cortex, a tissue which is not thought to contain CA cells in vivo. Cortical neurons were cultured with their non-neuronal constituents and 48 hr later immunostained for TH. Fibroblasts or glia had no effects, however...