نتایج جستجو برای: thalassemia intermedia
تعداد نتایج: 23663 فیلتر نتایج به سال:
Background In thalassemia intermedia (TI) patients no observational study prospectively evaluated in the real life the efficacy of the desferrioxamine (DFO) therapy in removing or preventing myocardial iron overload. The efficacy endpoint of this study is represented by the changes in cardiac T2* values and left ventricular (LV) function parameters in non-transfusion dependent (NTD) TI patients...
The inherited diseases of hemoglobin have remarkable phenotypic variability because of genetic modifiers necessitating medical intervention at various stages of disease. Genotype–phenotype relationship is crucial in this regard. So three year retrospective study of biochemical pattern of Hemoglobinopathies and Thalassemias and their clinical manifestations was done in a cohort of 689 patients i...
Increased HbA2 is a characteristic finding in minor beta thalassemia. Minor β-thalassemia is a heterozygote form of β-thalassemia that carries thalassemia genes but does not cause thalassemia disease. Diagnosis of carriers is done by CBC, RBC Index, and HbA2 test. Very few cases of people with minorthalassemia have a normal HbA2. According to the results of this pilot study it seams that percen...
background: the advances in treatment regimes for thalassemic patients have increased the survival among them therefore osteoporosis has emerged as an important cause of morbidity. the aim of this study was to determine the prevalence of osteoporosis and osteopenia in patients with thalassemia from zafar adult thalassemia clinic, tehran, iran. patients and methods: in this cross sectional inves...
OBJECTIVES Chelating agents remain the mainstay in reducing the iron burden and extending patient survival in homozygous beta-thalassemia but adverse and toxic effects may increase with the institution and long term use of this essential therapy. This study aimed to estimate the incidence of deferasirox (DFX) side effects in patients with thalassemia major or intermedia. METHODS A retrospecti...
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