ous cells and tissues of mammals, and their physiological properties have been studied.]} TGases derived from animals are calcium ion-dependent enzymes, and are distributed in most organs, skin, and blood. To date, for example, guinea pig liver TGase,2) human epidermis keratinocyte TGase,3) and human blood coagulation factor XIII`) have been reported. TGases, the activities ef which were indepe...

The amino acid lysine is an agent that has been proposed for treating the clinical symptoms of recurrent herpes simplex labialis. This study examined the efficacy of long-term prophylactic lysine supplementation. Twenty-six volunteers with a history of frequently recurring herpetic lesions completed a 12-month double-blind crossovers study. The experimental group received daily oral supplements...