AIM To analyze the success of three different treatment modalities for heroin addiction: methadone therapy, hospital therapy without methadone, and therapeutic community. METHODS Ninety heroin addicts from the city of Split, Croatia, were systematically allocated to three groups, with 30 participants each, according to the addiction treatment modality they underwent or treatment that resulted...

BACKGROUND Concern Worldwide is an international humanitarian nongovernmental organization that piloted and is now implementing and researching community-based therapeutic care (CTC) approaches to managing acute malnutrition. Experience in several countries suggests that there are key issues to be addressed at the international, national, regional, and community levels for community-based treat...

OBJECTIVES Therapeutic hypothermia (TH) has been shown to improve survival and neurological outcome in patients resuscitated after out of hospital cardiac arrest (OHCA) from ventricular fibrillation/ventricular tachycardia (VF/VT). We evaluated the effects of using a TH protocol in a large community hospital emergency department (ED) for all patients with neurological impairment after resuscita...

We are never alone. Humans coexist with diverse microbial species that live within and upon us--our so-called microbiota. It is now clear that this microbial community is essentially another organ that plays a fundamental role in human physiology and disease. Basic and translational research efforts have begun to focus on deciphering mechanisms of microbiome function--and learning how to manipu...

On October 29, 2010, the U.S. FDA approved ceftaroline fosamil, a new cephalosporin with extended Gram positive coverage, for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia (CABP). Unlike the currently available cephalosporins, ceftaroline maintains bactericidal activity against multi-drug resistant Gram positive pathogens like MRS...