This paper describes an experimental test of the uni®ed theory of thermal shock. A borosilicate glass (78.1%SiO2± 13.3%B2O3±4.7%Na2O±3.4%Al2O3) subjected to ion-exchange in molten KNO3, was used. The theory predicts the critical temperature di€erence for fracture initiation by thermal shock; however, it overestimates the number of cracks which propagate simultaneously. Despite that fact, taken ...

Previously, we proposed a dual control mechanism for the regulation of the heat shock response in mammalian cells: a positive control mediated by the heat shock transcription factor HSF1 and a negative control mediated by the constitutive heat shock element-binding factor (CHBF). To study the physiological role of CHBF in the regulation of heat shock response, we purified CHBF to apparent homog...

We present results of semi-analytic calculations which show clear evidence for changes in the nonequilibrium ionization behind a supernova remnant forward shock undergoing efficient diffusive shock acceleration (DSA). The efficient acceleration of particles (i.e., cosmic rays) lowers the shock temperature and raises the density of the shocked gas, thus altering the ionization state of the plasm...

We have investigated the role of the double-stranded RNA-dependent protein kinase gene (pkr) in the regulation of the heat shock response. We show that the pkr gene is essential for efficient activation of the heat shock response and that pkr disruption profoundly inhibits heat shock protein 70 (HSP70) synthesis and blocks the development of thermotolerance. Despite these profound effects, pkr ...

The eradication of Trichophyton rubrum has been attempted via laser irradiation because it could result advantageous relative to current clinical therapies. Anticipating that the necessary thermal effects could unintentionally damage the underlying toe dermal layer, we have explored two auxiliary approaches: (a) laser irradiation under vacuum pressure, with and without water dousing and, (b) co...

The current status and needs of thermal biology and physiol ogy as related to clinical hyperthermia are summarized. Empha sis is placed on heat-induced modification of blood flow and microenvironment in tissues, on the biological effects of heat and X-rays, and on the relationship between drug resistance, heat resistance, and thermotolerance in thermochemotherapy. Re sults from recent studies i...

An yttria stabilised zirconia which exhibits a coreshell microstructure was investigated as a method to produce a zirconia with high ionic conductivity and improved thermal shock resistance. Zirconia grains consist of an outer shell of tetragonal zirconia with an inner core of monoclinic phase zirconia. Impedance spectroscopy was used to identify the e€ect of processing conditions on the grain ...

Forging dies at high temperatures are under contact pressure, variable mechanical loads and thermal shock, furthermore they should withstand wear and friction in a high level. So, in order to increase die life, the selection of die material, coating and hardness is essential. In this review, various methods used for die life enhancement such as carbide coating, using the super alloy stellite 6 ...

Physiological responses to temperature reflect the evolutionary adaptations of organisms to their thermal environment and the capability of animals to tolerate thermal stress. Contrary to conventional metabolism theory, increasing environmental temperatures have been shown to reduce metabolic rate in rocky-eulittoral-fringe species inhabiting highly variable environments, possibly as a strategy...

We present new results on the shock around the south-west radio lobe of Centaurus A using data from the Chandra Very Large Programme observations (740 ks total observing time). The X-ray spectrum of the emission around the outer south-western edge of the lobe is well described by a single power-law model with Galactic absorption – thermal models are strongly disfavoured, except in the region cl...