The roots of modern medicine can be traced back to the 5th century BC when Hippocratic rational medicine originated on the Greek islands of Cos and Cnidos. In this study we examine the way in which practitioners conducted their profession in Graeco-Roman times, as well as their training. Medical training was by way of apprenticeship with recognized doctors, but no qualifying examinations existe...

Alzheimer's disease (AD) is considered the "disease of the twenty-first century." With a 10-fold increase in global incidence over the past 100 years, AD is now reaching epidemic proportions and by all projections, AD patient numbers will continue to rise. Despite intense research efforts, AD remains a mystery and effective therapies are still unavailable. This represents an unmet need resultin...

In Late Antiquity Arabia, under the Byzantine and Sassanid states, there are many decentralized nomadic or sedentary tribal political structures in addition to centralized organizations. There constant conflicts wars between tribes. reasons for their such as booty, blood feud, revenge, border violations. All these relative multiplicity of show that inter-tribal a form life pre-Islamic period. T...

The article is devoted to the history of settlement Pripyat Polesye in 1st millennium AD. main attention paid monuments first half AD, their dating and cultural identity. It noted that at present source study base does not allow reliably “make ancient” Slavic Prague culture Polesie until IV century. associate it with post-Zarubinets circle. At end III century BC tribes Zarubintsy came territory...

We report here the complete genome sequence of Rhizobium sp. strain ACO-34A, isolated from Agave americana L. rhizosphere. No common nod genes were found, but there were nif genes for nitrogen fixing. A low average nucleotide identity to reported species supports its designation as a novel Rhizobium species that has a complete ribosomal operon in a plasmid.

Memantine is a noncompetitive moderate-affinity strong voltage-dependent N-methyl-D-aspartate receptor antagonist. It has been used to treat Alzheimer's disease (AD) since 1989. In 2018, it became the second most commonly drug for treatment of dementia in world. AD nonreversible, and memantine can only relieve symptoms but not cure it. Over past half-century, memantine's research clinical appli...