the activity of the magnocellular neurons (mcns) of supraoptic nucleus (son) is regulated by a variety of excitatory and inhibitory inputs. opioids are one of the important compounds that affect these inputs at son synapses. in this study, whole-cell patch clamp recording of son neurons was used to investigate the effect of acute and repeated morphine administration on spontaneous inhibitory an...

The case report on cotrimoxazole-induced pancreatitis by Versleijen et al. deals with the assessment of the probability that cotrimoxazole induced the acute pancreatitis: a causality assessment. In this editorial, we comment on this assessment from a clinical, pharmacological and epidemiological perspective. Moreover, the consequences of the results of the assessment are discussed.

1. The network topology is characterized in the language of graph theory (e.g. tree, 0-chain, 1-chain) [1] [2]. By this means, the set of steady-state fluxes can be parameterized explicitly. 2. A particular steady-state solution is selected. This steady-state solution is used to generate a nominal, stationary routing algorithm for the stochastic flow problem. 3. However, to ensure the network o...

The flow of Marxism was one of the most powerful social-political currents of the Pahlavi opposition which, despite the progress of political upheavals and internal splits, reached the threshold of the Islamic Revolution. One of the main reasons for the success of this flow, compared to other rival currents, was the presence of numerous symbols in the context of this adventure. The symbols of t...

We investigate SU(2) lattice gauge theory in four dimensions in the maximally abelian projection. Studying the effects on different lattice sizes we show that the deconfinement transition of the fields and the percolation transition of the monopole currents in the three space dimensions are precisely related. To arrive properly at this result the uses of a mathematically sound characterization ...

When metamorphosed Cases will almost certainly cease to be a journal. We tried the journal model initially because we thought that people wanted to publish in journals -even though it's an increasingly archaic and cumbersome form that requires expensive apparatus. Academics are showing themselves willing to write blogs and publish on "databases" like PLoS One, PloS Currents, and Nature Communic...

PETER A. GOLDSTEIN, FRANK P. ELSEN, SHUI-WANG YING, CAROLYN FERGUSON, GREGG E. HOMANICS, AND NEIL L. HARRISON C. V. Starr Laboratory for Molecular Neuropharmacology, Department of Anesthesiology, Weill Medical College, Cornell University, New York, New York 10021; and Department of Anesthesiology and Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvan...