We developed a unidirectional 45Ca2+ efflux technique in which 60 cumulative doses of inositol 1,4,5-trisphosphate (InsP3), each lasting 6 s, were subsequently added to permeabilized A7r5 cells. This technique allowed an accurate determination of the threshold for InsP3 action, which was around 32 nM InsP3 under control conditions. The InsP3-induced Ca2+ release was characterized by an initial ...

The supply and threshold voltage scaling has been proposed for low-voltage/low-power design [1, 2, 3]. The programmable floating-gate circuits [3, 4] can be used to implement low-voltage/low-power digital circuits. The threshold voltages are shifted using reversed supply voltages and UV-light. The supply voltage may be reduced and the current level is determined by the threshold shift. Before t...

The latency of visual responses generally decreases as contrast increases. Recording in the lateral geniculate nucleus (LGN), we find that response latency increases with increasing contrast in ON cells for some visual stimuli. We propose that this surprising latency trend can be explained if ON cells rest further from threshold at higher contrasts. Indeed, while contrast changes caused a combi...

the mössbauer spectra of nanoferrite materials such as ni0.25mn0.75fe2o4, co0.5mn0.5fe2o4 and ni0.4co0.6fe2o4 have been reported and the above materials were prepared by sol-gel combustion method using metal nitrates as source material and polyvinyl alcohol(pva) as agglomeration reducing agent. as the structural, thermal and magnetic properties (vsm) of the above ferrites have been published al...