BACKGROUND AND OBJECTIVES Among the array of microangiopathies that may occur during pregnancy, HELLP syndrome and thrombotic thrombocytopenic purpura (TTP) produce similar laboratory findings (hemolytic anemia and thrombocytopenia), although neurological symptoms prevail in TTP and abnormal liver function in HELLP syndrome. It is clinically important to distinguish the two entities given that ...

a Logistics & Supply Chain Management Department, Universidad Popular Autónoma del Estado de Puebla. 17 Sur 901, Barrio de Santiago, 72410 Puebla, Puebla, México. Calle 48 y 116, (1900) La Plata, Argentina Email: [email protected] b Optimization Group Applied Math Laboratory MAIAA, Ecole Nationale de l'Aviation Civile 7, Ave. Ed Belin 31055 Toulouse, France Email: [email protected]...

The syndrome of thrombotic microangiopathic haemolytic anaemia is rare and almost all the cases reported have been in adults. Very few cases occurring in childhood have been reported and the youngest recorded case was 22 months old (Craig and Gitlin, 1957). We report the clinical and pathological details and the response to treatment of a child aged 21 months, who was seen at the Austin Hospita...

The microvascular endothelium of the kidney glomerulus is injured in Shiga-like toxigenic bacterial infection, genetic or acquired loss of complement regulatory protein function, and allo-immune responses of solid-organ or bone marrow transplantation. Existing models of diseases with glomerular endothelial cell (EC) injury, collectively grouped as thrombotic microangiopathies, are problematic, ...