Thyroid disease commonly affects women of childbearing age and is the second most common endocrinological disorder diagnosed in pregnancy after gestational diabetes. In normal gestation, the thyroid gland adapts its structure and function to satisfy increasing functional demand. The marked physiological changes that occur during normal pregnancy make it necessary to use specific reference range...

BACKGROUND & OBJECTIVES Abnormalities in thyroid hormonal status is common in major psychiatric disorders. Although the relevance of thyroid dysfunction to bipolar disorder is well-recognized, yet the association between thyroid dysfunction and schizophrenia-spectrum disorders is under-emphasized. The aim of this study was to examine and compare the rates of abnormal thyroid hormonal status in ...

OBJECTIVE An association between diabetes mellitus and autoimmune thyroid disease is well known. We have investigated the prevalence of thyroid dysfunction and autoimmunity in type 1 diabetic patients. METHODS Seventy-nine type 1 diabetic patients were recruited in the study, and underwent complete investigations for thyroid function, which included free thyroxine, free tri-iodothyronine, and...

OBJECTIVE To determine the frequency of thyroid dysfunction in patients of chronic hepatitis C during treatment with interferon alpha-2b and ribavirin therapy. STUDY DESIGN A cohort study. PLACE AND DURATION OF STUDY Army Medical College and Military Hospital, Rawalpindi, from February 2006 to January 2007. METHODOLOGY One hundred and sixty seven non-cirrhotic chronic hepatitis C patients...

Amiodarone, used in the treatment of cardiac arrhythmias, is associated with thyroid dysfunction. No reports exist on its frequency in southern Brazil, nor studies evaluating the usefulness of clinical scores to diagnose thyroid abnormalities in these patients. This study aimed at determining the prevalence of amiodarone-induced thyroid dysfunction in a representative sample from a tertiary cen...

Objective. To determine the association of thyroid dysfunction with the severity of the disease and response to treatment in patients of chronic hepatitis C. Design. Cohort study. Patients. One hundred and sixty seven noncirrhotic chronic hepatitis C patients were grouped into treatment group (n = 107) and control group (n = 60). Measurements. Baseline S. ALT and S. AST by IFCC and S. TSH, S. f...

Mean platelet volume (MPV) and platelet distribution width (PDW) are morphometric indices of size distribution and variability of platelet. We aimed to explore the associations between MPV or PDW and thyroid function in a large Chinese cohort.This was a cross-sectional study with a recruitment of 13,622 self-reported healthy Chinese (8424 males, 5198 females). Clinical data of the participants ...

objective: diabetes mellitus and thyroid disease are the two common endocrinopathies seen in adult population. studies to evaluate thyroid disorders in patients with type 2 diabetes are lacking. the aim of this study was to compare prevalence of thyroid dysfunction and autoim-munity in type 2 diabetic patients with age and sex matched non-diabetic control group. material and methods: among pati...

Timely treatment of thyroid disease during pregnancy is important in preventing adverse maternal and fetal outcomes. Thyroid abnormalities are very often subclinical in nature and not easily recognized without specific screening programs. Even mild maternal thyroid hormone deficiency may lead to neurodevelopment complications in the fetus. The main diagnostic indicator of thyroid disease is the...

Background: Significant incidence of thyroid dysfunction, especially hypothyroidism, has been reported in Kashmir Valley of India. There is a paucity of studies that assessed the presence of thyroid dysfunction in various age groups of people in Srinagar. Objectives: This study aimed to investigate the prevalence of thyroid dysfunction in the local population who visit the outpatient department...