1. This study was carried out to investigate the effects of 1, 25-dihydroxycholecalciferol (1, 25 (OH)2 D3) and a hydroalcoholic extract of Withania somnifera (WS) root on performance, mineral retention, bone mineralisation, bone mechanical and bone histological characteristics of broiler chicks. 2. A 2 × 3 × 2 factorial experiment consisted of a positive control diet with adequate Ca and a neg...

OBJECTIVE The objective of this study was to evaluate the effectiveness of the treatment of infected nonunion of tibia and femur by bone transport. MATERIAL AND METHODS We retrospectively reviewed 110 patients with infected nonunion of tibia and femur treated by bone transport. Our study included 92 males and 18 females with a mean age of 38.90 years. The site of infected nonunion involved 72...

We measured the extent and rate of new bone formation over an 18-month period before, during and after the lengthening of ten leg segments in six patients aged between 8 and 18 years, using dual-energy X-ray absorptiometry (DEXA). New bone formation could be identified within one week of the start of distraction. As lengthening proceeded, the bone density of the gap fell, reaching minimum value...

Background: Distal tibia fractures are among the most common bony injuries, with a significant rate of nonunion anddelayed union. There are multiple methods for the management of distal tibia fractures. Among the plating methods,there are bridge plating and compression plating techniques. There is still a lack of evidence about whether one methodhas a higher rate of union than...

Some studies based on bone biopsy have demonstrated that in patients with tumor-induced osteomalacia (TIO) the mineralization process of matrix is profoundly disturbed. However, interrelationship between clinical and biochemical features microarchitecture this disease needs further analysis. With purpose mind, we set out three objectives: (i) to determine estimated strength a group using high-r...

Many fractures occur in individuals without osteoporosis defined by areal bone mineral density (aBMD). Inclusion of other aspects of skeletal strength may be useful in identifying at-risk subjects. We used surrogate measures of bone strength at the radius and tibia measured by peripheral quantitative computed tomography (pQCT) to evaluate their relationships with nonvertebral fracture risk. Fem...

BACKGROUND Bone can adjust its morphological structure to adapt to the changes of mechanical environment, i.e. the bone structure change is related to mechanical loading. This implies that osteoarthritis may be closely associated with knee joint deformity. The purposes of this paper were to simulate the internal bone mineral density (BMD) change in three-dimensional (3D) proximal tibia under di...

OBJECTIVES The purposes of this study were to examine tibia bone density and geometry in young and middle aged men, and to explore relationships between pQCT- and DXA-derived body composition variables. METHODS Healthy males (18-30 years old, n=31; 50-64 years old, n=37) had their total body areal bone mineral density (aBMD) and body composition measured with Dual Energy X-ray Absorptiometry ...

INTRODUCTION Osteoporosis of the axial skeleton is a known complication of ankylosing spondylitis (AS), but bone loss affecting the peripheral skeleton is less studied. This study on volumetric bone mineral density (vBMD) and bone microarchitecture in AS was conducted to compare peripheral vBMD in AS patients with that in healthy controls, to study vBMD in axial compared with peripheral bone, a...

Mechanobiology In article 2201830 by Lining Arnold Ju and co-workers, a 3D-rendered tibia bone, featuring an observation window located in its diaphysis region, reveals bone marrow that is abundant vasculature. During exercise, the central arteries transverse arterioles experience substantial surface stresses, which are then transferred from cortical to more pliable through process known as mec...