PURPOSE Interestingly, prostate-specific antigen (PSA), which is used to monitor prostate disorders, has been suggested to be beneficial in estimating prognosis associated with coronary artery disease (CAD). The aim of the present study was to investigate the relationship of serum levels of PSA and free PSA (fPSA) with prognosis of acute coronary syndromes (ACS), extent of CAD and major adverse...

AIM The aim of this paper was to investigate the value of Global Registry of Acute Coronary Events (GRACE) and thrombolysis in myocardial infarction (TIMI) risk scores for risk stratification and prognosis in female patients with non-ST segment elevation acute coronary syndrome (NSTE-ACS). METHODS Non-elderly (<65 years) and elderly (≥65 years) female patients with NSTE-ACS (totally 869 cases...

OBJECTIVE To determine the long-term prognostic value of stress imaging and clinical risk scoring for cardiovascular mortality in chest pain patients after ruling out acute coronary syndrome (ACS). METHODS A standard rule-out protocol was performed in emergency room patients with a normal or non-diagnostic admission electrocardiogram (ECG) within 6 h of chest pain onset. ACS patients were ide...

BACKGROUND Diagnosis of coronary artery disease in women is more difficult because of lower specificity of symptoms and diagnostic accuracy of noninvasive testing. We sought to examine the relationship between gender and cardiac biomarkers in patients with unstable angina (UA)/non-ST-segment elevation myocardial infarction (NSTEMI). METHODS AND RESULTS In the TACTICS-TIMI 18, OPUS-TIMI 16, an...

in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials. JAMA 2005;293:2908–2917. 5. Antman EM, Cohen M, Bernink PJ, McCabe CH, Horacek T, Papuchis G, Mautner B, Corbalan R, Radley D, Braunwald E. The TIMI risk score for unstable angina/non-ST-elevation MI: a method for prognostication and therapeutic decision making. JAMA 2000;284:835–842. 6. Yan AT, Yan R...

BACKGROUND The manifestations, complications, and outcomes of cardiovascular disease differ between women and men. The safety and efficacy of pharmacological reperfusion therapy in women with ST-elevation myocardial infarction are of particular interest. METHODS AND RESULTS We investigated outcomes in the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment-Thromb...

he benefits of glycoprotein (GP) IIb/IIIa inhibitors are ell established for patients with an acute coronary synrome (ACS) treated with an early invasive strategy, espeially in the presence of high-risk features (troponin posiivity, ST-segment depression on presentation, recurrent schemia, or high TIMI [Thrombolysis In Myocardial nfarction] risk score) (1). These benefits exists even in the res...

OBJECTIVES The purpose of this research was to determine if sex and gender differences in the management of acute coronary syndromes (ACS) are associated with differences in prognosis after ACS. BACKGROUND Previous investigators have reported sex/gender differences in the management of patients with ACS, but the impact of these differences on prognosis is unclear. METHODS We analyzed data f...